E-Cigarette Use: Device Market, Study Design, and Emerging Evidence of Biological Consequences.
E-Cigarette Use: Device Market, Study Design, and Emerging Evidence of Biological Consequences.
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DOI：
10.3390/ijms222212452
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发表时间：
2021-11-18
影响因子：
5.6
通讯作者：
Bennewitz MF
中科院分区：
文献类型：
--
作者：
Snoderly HT;Nurkiewicz TR;Bowdridge EC;Bennewitz MF
Electronic cigarettes are frequently viewed as a safer alternative to conventional cigarettes; however, evidence to support this perspective has not materialized. Indeed, the current literature reports that electronic cigarette use is associated with both acute lung injury and subclinical dysfunction to the lung and vasculature that may result in pathology following chronic use. E-cigarettes can alter vascular dynamics, polarize innate immune populations towards a proinflammatory state, compromise barrier function in the pulmonary endothelium and epithelium, and promote pre-oncogenic phenomena. This review will summarize the variety of e-cigarette products available to users, discuss current challenges in e-cigarette study design, outline the range of pathologies occurring in cases of e-cigarette associated acute lung injury, highlight disease supporting tissue- and cellular-level changes resulting from e-cigarette exposure, and briefly examine how these changes may promote tumorigenesis. Continued research of the mechanisms by which e-cigarettes induce pathology benefit users and clinicians by resulting in increased regulation of vaping devices, informing treatments for emerging diseases e-cigarettes produce, and increasing public awareness to reduce e-cigarette use and the onset of preventable disease.
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影响因子：
4.6
作者：
Canistro D;Vivarelli F;Cirillo S;Babot Marquillas C;Buschini A;Lazzaretti M;Marchi L;Cardenia V;Rodriguez-Estrada MT;Lodovici M;Cipriani C;Lorenzini A;Croco E;Marchionni S;Franchi P;Lucarini M;Longo V;Della Croce CM;Vornoli A;Colacci A;Vaccari M;Sapone A;Paolini M
通讯作者：
Paolini M
影响因子：
6.2
作者：
Borderud SP;Li Y;Burkhalter JE;Sheffer CE;Ostroff JS
通讯作者：
Ostroff JS
影响因子：
4.1
作者：
Bitzer, Zachary T.;Goel, Reema;Richie, John P., Jr.
通讯作者：
Richie, John P., Jr.
DOI：
10.1152/ajplung.00304.2018
发表时间：
2019-03-01
影响因子：
4.9
作者：
Clapp, Phillip W.;Lavrich, Katelyn S.;Jaspers, Ilona
通讯作者：
Jaspers, Ilona
DOI：
10.1152/ajplung.00564.2017
发表时间：
2019-01-01
影响因子：
4.9
作者：
Ahmad, Shama;Zafar, Iram;Ahmad, Aftab
通讯作者：
Ahmad, Aftab