The host-cell architectural protein HMG I(Y) modulates binding of herpes simplex virus type 1 ICP4 to its cognate promoter.
The host-cell architectural protein HMG I(Y) modulates binding of herpes simplex virus type 1 ICP4 to its cognate promoter.
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宿主细胞结构蛋白 HMG I(Y) 调节 1 型单纯疱疹病毒 ICP4 与其同源启动子的结合。
DOI：
10.1006/viro.1999.9607
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发表时间：
1999
期刊：
影响因子：
--
通讯作者：
Silverstein,SJ
中科院分区：
文献类型：
--
作者：
Panagiotidis,CA;Silverstein,SJ
The productive infection cycle of herpes simplex virus is controlled in part by the action of ICP4, an immediate-early gene product that acts as both an activator and repressor of transcription. ICP4 is autoregulatory, and IE-3, the gene that encodes it, contains a high-affinity binding site for the protein at its cap site. Previously, we had demonstrated that this site could be occupied by proteins found in nuclear extracts from uninfected cells. A HeLa cell cDNA expression library was screened with a DNA probe containing the IE-3 gene cap site, and clones expressing the architectural chromatin proteins HMG I and HMG Y were identified by this technique. HMG I is shown to augment binding of ICP4 to its cognate site inin vitroassays and to enhance the activity of this protein in short-term transient expression assays.
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ICP4 与细胞/感染细胞因子的相互作用及其磷酸化状态调节单纯疱疹病毒 DNA 中前导序列的差异识别。
影响因子：
11.4
作者：
A. Papavassiliou;K. Wilcox;S. Silverstein
通讯作者：
S. Silverstein
高迁移率族蛋白 HMG-I(Y) 的完整鼠 cDNA 序列、基因组结构和组织表达。
影响因子：
4.8
作者：
Kenneth R. Johnson;Donald A. Lehnt;Terry;Eltonll;Philip;Barr;Raymond Reeves
通讯作者：
Raymond Reeves
1型纤溶酶原激活剂抑制基因：其启动子的功能分析和糖皮质激素调控。
DOI：
10.1073/pnas.85.15.5525
发表时间：
1988
影响因子：
11.1
作者：
vanZonneveld,AJ;Curriden,SA;Loskutoff,DJ
通讯作者：
Loskutoff,DJ
影响因子：
5.6
作者：
J. Mote;Pejman Ghanouni;D. Reines
通讯作者：
J. Mote;Pejman Ghanouni;D. Reines
影响因子：
10.5
作者：
SANDRIGOLDIN, RM;MENDOZA, GE
通讯作者：
MENDOZA, GE