Clinical and virological features of first human monkeypox cases in Germany.
Clinical and virological features of first human monkeypox cases in Germany.
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DOI：
10.1007/s15010-022-01874-z
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发表时间：
2023-03
期刊：
影响因子：
7.5
通讯作者：
Woelfel, Roman
中科院分区：
文献类型：
--
作者：
Noe, Sebastian;Zange, Sabine;Seilmaier, Michael;Antwerpen, Markus H.;Fenzl, Thomas;Schneider, Jochen;Spinner, Christoph D.;Bugert, Joachim J.;Wendtner, Clemens-Martin;Woelfel, Roman
猴痘是一种人畜共患的正痘病毒感染，在中非和西非流行。 2022年5月，欧洲和北美多国爆发人类猴痘感染，包括人际传播。在这里，我们介绍了德国诊断的前两例人类猴痘感染病例。我们提供临床和病毒学研究结果，包括血液和精液中猴痘病毒 DNA 的检测。我们患者的临床表现和病史表明，性行为期间的密切身体接触是感染途径。猴痘需要快速诊断并迅速做出公共卫生反应。目前情况下应考虑该病，尤其是水疱或脓疱性皮疹的鉴别诊断，尤其是频繁性接触的患者。最重要的是，必须提高所有卫生专业人员的认识，以快速、正确地识别和诊断这种疾病，这种疾病在欧洲可能仍未得到充分报告（Adler 等人，发表于 Lancet Infect Dis https://doi.org/10.1016/s1473-3099(22)00228-6, 2022）。
Monkeypox is a zoonotic orthopoxvirus infection endemic in central and western Africa. In May 2022, human monkeypox infections including human-to-human transmission were reported in a multi-country outbreak in Europe and North America. Here we present the first two cases of monkeypox infection in humans diagnosed in Germany. We present clinical and virological findings, including the detection of monkeypox virus DNA in blood and semen. The clinical presentation and medical history of our patients suggest close physical contact during sexual interactions as the route of infection. Monkeypox requires rapid diagnosis and prompt public health response. The disease should be considered in the current situation especially the differential diagnosis of vesicular or pustular rash, particularly in patients with frequent sexual contacts. Most importantly, it is essential to raise awareness among all health professionals for the rapid and correct recognition and diagnosis of this disease, which is probably still underreported in Europe (Adler et al. in Lancet Infect Dis https://doi.org/10.1016/s1473-3099(22)00228-6, 2022).
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DOI：
10.1093/infdis/jiaa559
发表时间：
2022-04-19
期刊：
The Journal of infectious diseases
影响因子：
--
作者：
通讯作者：
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影响因子：
5.4
作者：
BLASCO, R;MOSS, B
通讯作者：
MOSS, B
2001年至2018年之间，中非共和国的人类猴痘的基因组史。
影响因子：
4.6
作者：
Berthet N;Descorps-Declère S;Besombes C;Curaudeau M;Nkili Meyong AA;Selekon B;Labouba I;Gonofio EC;Ouilibona RS;Simo Tchetgna HD;Feher M;Fontanet A;Kazanji M;Manuguerra JC;Hassanin A;Gessain A;Nakoune E
通讯作者：
Nakoune E
DOI：
10.15585/mmwr.mm7114a1
发表时间：
2022-04-08
期刊：
MMWR. Morbidity and mortality weekly report
影响因子：
--
作者：
Rao AK;Schulte J;Chen TH;Hughes CM;Davidson W;Neff JM;Markarian M;Delea KC;Wada S;Liddell A;Alexander S;Sunshine B;Huang P;Honza HT;Rey A;Monroe B;Doty J;Christensen B;Delaney L;Massey J;Waltenburg M;Schrodt CA;Kuhar D;Satheshkumar PS;Kondas A;Li Y;Wilkins K;Sage KM;Yu Y;Yu P;Feldpausch A;McQuiston J;Damon IK;McCollum AM;July 2021 Monkeypox Response Team
通讯作者：
July 2021 Monkeypox Response Team
影响因子：
56.3
作者：
Adler, Hugh;Gould, Susan;Hine, Paul;Snell, Luke B.;Wong, Waison;Houlihan, Catherine F.;Osborne, Jane C.;Rampling, Tommy;Beadsworth, Mike Bj;Duncan, Christopher Ja;Dunning, Jake;Fletcher, Tom E.;Hunter, Ewan R.;Jacobs, Michael;Khoo, Saye H.;Newsholme, William;Porter, David;Porter, Robert J.;Ratcliffe, Libuse;Schmid, Matthias L.;Semple, Malcolm G.;Tunbridge, Anne J.;Wingfield, Tom;Price, Nicholas M.
通讯作者：
Price, Nicholas M.