Developing novel organocatalyzed aldol reactions for the enantioselective synthesis of biologically active molecules.
Developing novel organocatalyzed aldol reactions for the enantioselective synthesis of biologically active molecules.
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DOI：
10.1055/s-0030-1260029
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发表时间：
2011-06
期刊：
影响因子：
--
通讯作者：
Zhao CG
中科院分区：
文献类型：
--
作者：
Bhanushali M;Zhao CG
Aldol反应是形成碳-碳键的重要方法之一。由于其重要性和实用性，过去已经用不同的方法实现了该反应的不对称版本。在过去的十年中，有机催化领域取得了重大进展。有机催化Aldol反应是有机催化反应中研究最多的反应之一，它已成为合成大量光学富集产物的有力工具。本文综述了近年来在有机催化羟醛缩合反应中对映选择性合成生物活性分子的研究进展。与我们的研究密切相关的文献也包括在内。
Aldol reaction is one of the most important methods for the formation of carbon-carbon bonds. Because of its significance and usefulness, asymmetric versions of this reaction have been realized with different approaches in the past. Over the last decade, the area of organocatalysis has made significant progresses. As one of most studied reactions in organocatalyses, organocatalyzed aldol reaction has emerged as a powerful tool for the synthesis of a large number of useful products in optically enriched forms. In this review, we summarize our efforts on the development of novel organocatalyzed aldol reactions for the enantioselective synthesis of biological active molecules. Literatures closely related to our studies are also covered.
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影响因子：
3.5
作者：
Cui, Peng;McCalmont, William F.;Macdonald, Timothy L.
通讯作者：
Macdonald, Timothy L.
DOI：
10.1073/pnas.1006509107
发表时间：
2010-11-30
影响因子：
11.1
作者：
Bock, Dominique Anna;Lehmann, Christian W.;List, Benjamin
通讯作者：
List, Benjamin
影响因子：
5.2
作者：
Dodda, Rajasekhar;Zhao, Cong-Gui
通讯作者：
Zhao, Cong-Gui
影响因子：
7.3
作者：
Bolognesi, ML;Bartolini, M;Melchiorre, C
通讯作者：
Melchiorre, C
影响因子：
4.3
作者：
Connon, Stephen J.
通讯作者：
Connon, Stephen J.