Tone-in-noise detection deficits in elderly patients with clinically normal hearing.

Tone-in-noise detection deficits in elderly patients with clinically normal hearing.
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DOI:
10.1016/j.amjoto.2018.09.012
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发表时间:
2019-01
影响因子:
2.5
通讯作者:
Salvi R
Salvi R
中科院分区:
医学3区
文献类型:
--
作者:
Ralli M;Greco A;De Vincentiis M;Sheppard A;Cappelli G;Neri I;Salvi R

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老年人最常见的抱怨之一是在嘈杂的环境中听不懂说话。在许多情况下,这些缺陷是由于年龄相关的听力损失;然而,一些在噪音中听力困难的老年人在临床上具有正常的纯音阈值。虽然噪声中的语音测试提供了信息,但它无法确定导致语音处理缺陷的特定频率。听神经病患者和隐性听力损失的动物模型表明,噪声中音阈值可能为那些表达困难但在安静时阈值正常的患者提供特定频率的信息。因此,我们的目标是确定噪声中音阈值是否可以作为检测年龄相关性听力障碍的有用指标,尽管听力阈值正常。我们通过测量11名老年(62.4+/−5岁)和21名年轻(23.1+/−2.2岁)临床阈值正常的患者的噪声中音阈值来验证这一假设。在安静的声场中,然后在20、30和40dBHL宽带噪声中测量纯音听阈。尽管听力正常(≤25dBHL),但老年患者在0.125、4和8 kHz的噪声中音阈值明显低于年轻患者。线性回归分析表明,在所有频率下,老年患者和年轻患者的掩蔽增长几乎相同。然而,除了接近1 kHz外,老年患者在低频和高频下的掩蔽量通常比年轻患者多10-18分贝。在“线路繁忙”模型和听神经纤维丢失的颞骨研究的背景下,讨论了掩蔽的频率依赖变化。
One of the most common complaints among the elderly is the inability to understand speech in noisey environments. In many cases, these deficits are due to age-related hearing loss; however, some of the elderly that have difficulty hearing in noise have clinically normal pure-tone thresholds. While speech in noise testing is informative, it fails to identify specific frequencies responsible for the speech processing deficit. Auditory neuropathy patients and animal models of hidden hearing loss suggest that tone-in-noise thresholds may provide frequency specific information for those patients who express difficulty, but have normal thresholds in quiet. Therefore, we aimed to determine if tone-in-noise thresholds could be a useful measure in detecting age-related hearing deficits, despite having normal audiometric thresholds. We tested this hypothesis by measuring tone-in-noise thresholds in 11 Old (62.4 +/− 5 years) and 21 Young (23.1 +/− 2.2 years) patients with clinically normal thresholds. Tone thresholds were measured in a quite sound field, then in 20, 30 and 40 dB HL broadband noise. Despite having normal hearing (thresholds ≤ 25 dB HL), the Old patients had significantly worse tone-in-noise thresholds than the Young patients at 0.125, 4, and 8 kHz. Linear regression analysis showed that the growth of masking in Old and Young patients was nearly identical at all frequencies. However, the amount of masking at low and high frequencies was typically 10–18 dB greater in the Old patients compared to the Young, except near 1 kHz. The frequency-dependent changes in masking are discussed in the context of a “line busy” model and temporal bone studies of auditory nerve fiber loss.
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