Prevalence of type 1 and type 2 diabetes among children and adolescents from 2001 to 2009.
Prevalence of type 1 and type 2 diabetes among children and adolescents from 2001 to 2009.
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DOI：
10.1001/jama.2014.3201
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发表时间：
2014-05-07
影响因子：
120.7
通讯作者：
Hamman, Richard F.
中科院分区：
文献类型：
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作者：
Dabelea, Dana;Mayer-Davis, Elizabeth J.;Saydah, Sharon;Imperatore, Giuseppina;Linder, Barbara;Divers, Jasmin;Bell, Ronny;Badaru, Angela;Talton, Jennifer W.;Crume, Tessa;Liese, Angela D.;Merchant, Anwar T.;Lawrence, Jean M.;Reynolds, Kristi;Dolan, Lawrence;Liu, Lenna L.;Hamman, Richard F.
尽管人们担心这是一种“流行病”，但有关美国种族和民族中1型或2型糖尿病患病率趋势的数据有限。评估2001至2009年间按性别、年龄和种族/民族划分的美国青年中1型和2型糖尿病患病率的变化。病例患者确定在4个地理区域和1个管理卫生保健计划。研究人口是由2001年和2009年过渡种族人口普查地理地点的人口估计和卫生计划的成员计数确定的。医生诊断的0至19岁青年1型糖尿病和10至19岁青年2型糖尿病的患病率(每1000人)。2001年，330万青年中有4958人被诊断为1型糖尿病，患病率为1.48/1000(95%可信区间，1.44-1.52)。2009年，340万青年中有6666人被诊断为1型糖尿病，患病率为1.93/1000(95%可信区间，1.88-1.97)。2009年，1型糖尿病在白人青年中的患病率最高(95%CI，2.48-2.62)，在美国印第安人青年中最低(0.35/1000，95%CI，0.26-0.47)，除发病率最低的人群(0-4岁和美洲印第安人)外，在所有性别、年龄和种族/族裔亚群中，1型糖尿病的患病率在2001年至2009年期间均有所上升。调整了确证的完整性，在过去的8年中，1型糖尿病患者增加了21.1%(95%可信区间，15.6%-27.0%)。2001年，170万青年中有588人被诊断为2型糖尿病，患病率为0.34/1000(95%可信区间，0.31-0.37)。2009年，180万人中有819人被诊断为2型糖尿病，患病率为0.46/1000(95%CI，0.43-0.49)。2009年，美国印第安人青年的2型糖尿病患病率为1.20‰(95%CI，0.96-1.51)；黑人青年为1.06‰(95%CI，0.93-1.22)；西班牙裔青年为0.79‰(95%CI，0.70-0.88)；白人青年为0.17‰(95%CI，0.15-0.20)。2001年至2009年期间，所有年龄段的男女以及白人、西班牙裔和黑人青年的人数都有显著增加，而亚太岛民和美洲印第安人的人数没有显著变化。调整了确证的完整性，2型糖尿病的总体增加了30.5%(95%可信区间，17.3%-45.1%)。2001至2009年间，在美国5个地区，儿童和青少年中1型和2型糖尿病的患病率均有所上升。需要进一步研究以确定这些增长的原因。
Despite concern about an “epidemic,” there are limited data on trends in prevalence of either type 1 or type 2 diabetes across US race and ethnic groups. To estimate changes in the prevalence of type 1 and type 2 diabetes in US youth, by sex, age, and race/ethnicity between 2001 and 2009. Case patients were ascertained in 4 geographic areas and 1 managed health care plan. The study population was determined by the 2001 and 2009 bridged-race intercensal population estimates for geographic sites and membership counts for the health plan. Prevalence (per 1000) of physician-diagnosed type 1 diabetes in youth aged 0 through 19 years and type 2 diabetes in youth aged 10 through 19 years. In 2001, 4958 of 3.3 million youth were diagnosed with type 1 diabetes for a prevalence of 1.48 per 1000 (95% CI, 1.44–1.52). In 2009, 6666 of 3.4 million youth were diagnosed with type 1 diabetes for a prevalence of 1.93 per 1000 (95% CI, 1.88–1.97). In 2009, the highest prevalence of type 1 diabetes was 2.55 per 1000 among white youth (95% CI, 2.48–2.62) and the lowest was 0.35 per 1000 in American Indian youth (95% CI, 0.26–0.47) and type 1 diabetes increased between 2001 and 2009 in all sex, age, and race/ethnic subgroups except for those with the lowest prevalence (age 0–4 years and American Indians). Adjusted for completeness of ascertainment, there was a 21.1% (95% CI, 15.6%–27.0%) increase in type 1 diabetes over 8 years. In 2001, 588 of 1.7 million youth were diagnosed with type 2 diabetes for a prevalence of 0.34 per 1000 (95% CI, 0.31–0.37). In 2009, 819 of 1.8 million were diagnosed with type 2 diabetes for a prevalence of 0.46 per 1000 (95% CI, 0.43–0.49). In 2009, the prevalence of type 2 diabetes was 1.20 per 1000 among American Indian youth (95% CI, 0.96–1.51); 1.06 per 1000 among black youth (95% CI, 0.93–1.22); 0.79 per 1000 among Hispanic youth (95% CI, 0.70–0.88); and 0.17 per 1000 among white youth (95% CI, 0.15–0.20). Significant increases occurred between 2001 and 2009 in both sexes, all age-groups, and in white, Hispanic, and black youth, with no significant changes for Asian Pacific Islanders and American Indians. Adjusted for completeness of ascertainment, there was a 30.5% (95% CI, 17.3%–45.1%) overall increase in type 2 diabetes. Between 2001 and 2009 in 5 areas of the United States, the prevalence of both type 1 and type 2 diabetes among children and adolescents increased. Further studies are required to determine the causes of these increases.
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影响因子：
16.2
作者：
Dabelea, Dana;Mayer-Davis, Elizabeth J.;Lamichhane, Archana P.;D'Agostino, Ralph B.;Liese, Angela D.;Vehik, Kendra S.;Narayan, K. M. Venkat;Zeitler, Phillip;Hamman, Richard F.
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Hamman, Richard F.
DOI：
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