Low-level cigarette smoking and longitudinal change in serum cholesterol among adolescents. The Berlin-Bremen Study.

Low-level cigarette smoking and longitudinal change in serum cholesterol among adolescents. The Berlin-Bremen Study.
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青少年中低水平吸烟和血清胆固醇的纵向变化。

DOI:
10.1001/jama.1988.03720190025025
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发表时间:
1988
期刊:
JAMA
影响因子:
--
通讯作者:
P. Lippert
P. Lippert
中科院分区:
--
文献类型:
--
作者:
J. Dwyer;G. Rieger;N. Semmer;R. Fuchs;P. Lippert

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目前的研究旨在确定吸烟者和不吸烟者在开始吸烟前血清高密度脂蛋白胆固醇 (HDL-C) 浓度是否存在差异,以及青少年在吸烟的前两年是否可以检测到 HDL-C 水平下降。 1983 年、1984 年和 1985 年,对来自德国两个城市的 691 名七年级和八年级学生(年龄范围:12 至 14 岁)进行了纵向观察,观察 HDL-C 水平和吸烟情况的变化; 82% 的基线时不吸烟。对于这些基线不吸烟者,在吸烟者和仍然不吸烟者之间没有发现基线 HDL-C 浓度存在差异。相比之下,那些在初次检查后一两年内成为轻度吸烟者(每周 1 至 39 支香烟)或中度吸烟者(每周大于或等于 40 支香烟)的人在随访中证明,相对于持续不吸烟者,平均 HDL-C 浓度较低,减少了 -0.016 mmol/L [SE = .035] (-0.6 mg/dL) [SE = 1.4]轻度吸烟者为 -0.114 mmol/L [SE = .064] (-4.4 mg/dL) [SE = 2.5] 为中度吸烟者。这些发现表明,短期接触低水平的香烟烟雾可能会导致动脉粥样硬化。
The current study was conducted to determine if smokers and nonsmokers differ in serum concentrations of high-density lipoprotein cholesterol (HDL-C) before smoking initiation and if a decline in HDL-C levels could be detected among adolescents during the first two years of smoking. Changes in HDL-C levels and smoking were observed longitudinally in 1983, 1984, and 1985 among 691 seventh and eighth graders (age range, 12 to 14 years) from two German cities; 82% were nonsmokers at baseline. For these baseline nonsmokers, no differences in baseline HDL-C concentrations were found between those who became smokers and those who remained nonsmokers. In contrast, those who became light (one to 39 cigarettes per week) or moderate (greater than or equal to 40 cigarettes per week) smokers by one or two years after the initial examination evidenced lower mean HDL-C concentrations relative to persistent nonsmokers at follow-up, constituting a decrement of -0.016 mmol/L [SE = .035] (-0.6 mg/dL) [SE = 1.4] for light smokers and -0.114 mmol/L [SE = .064] (-4.4 mg/dL) [SE = 2.5] for moderate smokers. These findings suggest that short-term exposure to cigarette smoke at low levels may have atherogenic consequences.
DOI: 10.1161/01.cir.72.5.971
发表时间: 1985-01-01
期刊: CIRCULATION
影响因子: 37.8
作者:
TELL, GS;GRIMM, RH;THEODORSEN, L
通讯作者: THEODORSEN, L
DOI: --
发表时间: 1986
期刊: JAMA
影响因子: --
作者:
DeLong,DM;DeLong,ER;Wood,PD;Lippel,K;Rifkind,BM
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DOI: 10.1093/oxfordjournals.aje.a113616
发表时间: 1983
影响因子: 5
作者:
Criqui,MH;Frankville,DD;Barrett-Connor,E;Klauber,MR;Holdbrook,MJ;Turner,JD
通讯作者: Turner,JD
DOI: --
发表时间: 1980
期刊: Circulation
影响因子: 37.8
作者:
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绝经后妇女体力活动与高密度脂蛋白胆固醇的关系。
DOI: 10.1016/0021-9681(86)90152-9
发表时间: 1986
期刊: Journal of chronic diseases
影响因子: --
作者:
Cauley,JA;LaPorte,RE;Sandler,RB;Orchard,TJ;Slemenda,CW;Petrini,AM
通讯作者: Petrini,AM