Networking chemical robots for reaction multitasking.

Networking chemical robots for reaction multitasking.
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DOI:
10.1038/s41467-018-05828-8
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发表时间:
2018-08-24
影响因子:
16.6
通讯作者:
Cronin L
Cronin L
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Caramelli D;Salley D;Henson A;Camarasa GA;Sharabi S;Keenan G;Cronin L

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物联网的发展导致了能够控制和计算的联网设备数量的爆炸式增长。然而,虽然这些方法在遥感中很常见,但由于难以开发足够灵活的实验数据收集系统,因此并没有影响化学。在这里,我们提出了一个简单的和负担得起的(<500美元)的化学能力的机器人与一套标准的硬件和软件协议,可以联网协调许多化学实验在真实的时间。我们演示了如何通过两个互联网连接的机器人协作完成多个过程,在单个机器人所需的一小部分时间内探索一组偶氮偶联反应,以及将信息编码和解码到振荡反应网络中。该系统还可用于评估化学反应的再现性,并通过游戏探索化学空间来发现新的反应结果。在实验室之间分配反应工作量可以更有效地解决化学问题,但开发可行的硬件和软件具有挑战性。在这里,作者提出了一个互联网连接的廉价机器人网络,可以执行化学反应,并在真实的时间分享结果,展示了一种数字化的化学合作方法。
The development of the internet of things has led to an explosion in the number of networked devices capable of control and computing. However, whilst common place in remote sensing, these approaches have not impacted chemistry due to difficulty in developing systems flexible enough for experimental data collection. Herein we present a simple and affordable (<$500) chemistry capable robot built with a standard set of hardware and software protocols that can be networked to coordinate many chemical experiments in real time. We demonstrate how multiple processes can be done with two internet-connected robots collaboratively, exploring a set of azo-coupling reactions in a fraction of time needed for a single robot, as well as encoding and decoding information into a network of oscillating reactions. The system can also be used to assess the reproducibility of chemical reactions and discover new reaction outcomes using game playing to explore a chemical space. Distributing a reaction workload across laboratories can solve chemical problems more efficiently, but it is challenging to develop viable hardware and software. Here, the authors present an internet-connected network of cheap robots that can perform chemical reactions and share outcomes in real time, demonstrating a digitized approach to chemical collaboration.
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