Advances in diffusion MRI acquisition and processing in the Human Connectome Project.

Advances in diffusion MRI acquisition and processing in the Human Connectome Project.
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DOI:
10.1016/j.neuroimage.2013.05.057
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发表时间:
2013-10-15
期刊:
影响因子:
5.7
通讯作者:
Behrens, Timothy E. J.
Behrens, Timothy E. J.
中科院分区:
医学1区
文献类型:
--
作者:
Sotiropoulos, Stamatios N.;Jbabdi, Saad;Xu, Junqian;Andersson, Jesper L.;Moeller, Steen;Auerbach, Edward J.;Glasser, Matthew F.;Hernandez, Moises;Sapiro, Guillermo;Jenkinson, Mark;Feinberg, David A.;Yacoub, Essa;Lenglet, Christophe;Van Essen, David C.;Ugurbil, Kamil;Behrens, Timothy E. J.

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人类连接组计划(HCP)是一个为期5年的合作项目,旨在绘制健康成年人的大脑连接及其变异性。一个由HCP研究者组成的联盟将使用多种成像方式,以及广泛的行为和遗传数据,对1200名健康成年人进行研究。在本综述中,我们重点关注扩散MRI (dMRI)和项目的结构连接方面。我们介绍了在获取和处理方面的最新进展,使我们能够获得非常高质量的体内MRI数据,同时能够扫描大量受试者。这些进展是在项目试点阶段对数据采集和处理的许多方面进行优化的2年密集努力的结果。这里描述的数据质量和方法代表了数据集和处理管道,这些数据集和处理管道将从2013年开始每季度向社区免费提供一次。
The Human Connectome Project (HCP) is a collaborative 5-year effort to map human brain connections and their variability in healthy adults. A consortium of HCP investigators will study a population of 1200 healthy adults using multiple imaging modalities, along with extensive behavioral and genetic data. In this overview, we focus on diffusion MRI (dMRI) and the structural connectivity aspect of the project. We present recent advances in acquisition and processing that allow us to obtain very high-quality in-vivo MRI data, while enabling scanning of a very large number of subjects. These advances result from 2 years of intensive efforts in optimising many aspects of data acquisition and processing during the piloting phase of the project. The data quality and methods described here are representative of the datasets and processing pipelines that will be made freely available to the community at quarterly intervals, beginning in 2013.
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