Impact of ferromanganese alloy plants on household dust manganese levels: implications for childhood exposure.
Impact of ferromanganese alloy plants on household dust manganese levels: implications for childhood exposure.
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DOI：
10.1016/j.envres.2015.01.019
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发表时间：
2015-04
影响因子：
8.3
通讯作者：
Smith, D. R.
中科院分区：
文献类型：
--
作者：
Lucas, E. L.;Bertrand, P.;Guazzetti, S.;Donna, F.;Peli, M.;Jursa, T. P.;Lucchini, R.;Smith, D. R.
生活在有铁锰合金植物活动的社区中的青少年已被证明表现出嗅觉和精细运动功能缺陷。家庭灰尘可能是儿童接触锰 (Mn) 的重要途径，尽管此前尚未测量灰尘中的锰浓度来评估铁锰合金工厂排放物对家庭的污染。在这里，我们确定了来自三个意大利社区的室内和室外家庭灰尘中锰和其他金属（铝、镉、铬、铜、铁、铅和锌）表面负载之间的关联，这三个社区的铁锰合金工厂活动历史不同：Bagnolo Mella，有一个活跃的铁锰合金工厂（n=178户）； Valcamonica，拥有历史上活跃的植物（n=166）；和加尔达湖，没有铁锰工厂活动的历史（n=99）。我们还评估了家庭儿童的其他环境（土壤、空气颗粒物）和候选生物标志物（血液、头发、唾液、指甲）样本中的锰水平。三个地点之间的家庭灰尘锰浓度和表面负载存在显着差异，巴尼奥洛梅拉的水平最高（室外锰浓度中值 = 4620，范围 487 - 183,000 µg/g），瓦尔卡莫尼卡居中（中值 = 876，范围 407 - 8240 µg/g），加尔达湖最低（中值 = 407，范围 258 - 7240 微克/克）。 Bagnolo Mella（而非其他社区）的室外灰尘锰浓度与距工厂的距离呈显着负相关（R2=0.6630，P<0.0001）。此外，室外灰尘锰浓度和负载量对室内灰尘锰浓度和负载量具有高度预测性，但显着高于室内灰尘锰浓度和负载量约2至约7倍（锰浓度）和约7至约20倍（锰负载量）。最后，室内和室外灰尘锰浓度和室外灰尘锰负荷值与土壤和空气锰浓度以及儿童头发和指甲的锰浓度高度显着相关，但与唾液或血液锰水平微弱或不相关。鉴于有证据表明锰暴露水平升高与儿童神经系统损伤有关，这些数据支持应降低受污染环境中的粉尘锰含量，以保护居住儿童的健康。
Adolescents living in communities with ferromanganese alloy plant activity have been shown to exhibit deficits in olfactory and fine motor function. Household dust may serve as an important manganese (Mn) exposure pathway to children, though dust Mn concentrations have not previously been measured to assess household contamination from ferromanganese alloy plant emissions. Here we determined the association between dust concentrations and surface loadings of Mn and other metals (Al, Cd, Cr, Cu, Fe, Pb, and Zn) in indoor and outdoor household dust from three Italian communities that differ by history of ferromanganese alloy plant activity: Bagnolo Mella, with an active ferromanganese alloy plant (n=178 households); Valcamonica, with historically active plants (n=166); and Garda Lake, with no history of ferromanganese plant activity (n=99). We also evaluated Mn levels in other environmental (soil, airborne particulates) and candidate biomarker (blood, hair, saliva, fingernails) samples from children within the households. Household dust Mn concentrations and surface loadings were significantly different between the three sites, with levels highest in Bagnolo Mella (outdoor median Mn concentration = 4620, range 487 – 183,000 µg/g), intermediate in Valcamonica (median = 876, range 407 – 8240 µg/g), and lowest in Garda Lake (median = 407, range 258 – 7240 µg/g). Outdoor dust Mn concentrations in Bagnolo Mella, but not the other communities, were significantly inversely related with distance from the plant (R2=0.6630, P<0.0001). Moreover, outdoor dust Mn concentrations and loadings were highly predictive of but significantly higher than indoor dust Mn concentrations and loadings by ~2 to ~7-fold (Mn concentrations) and ~7 to ~20-fold (Mn loadings). Finally, both indoor and outdoor dust Mn concentrations and outdoor dust Mn loading values were highly significantly correlated with both soil and air Mn concentrations, and with children’s hair and fingernail Mn concentrations, but weakly or not associated with saliva or blood Mn levels. Given the evidence associating elevated Mn exposure with neurological impairments in children, these data support that dust Mn levels should be reduced in contaminated environments to protect the health of resident children.
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影响因子：
10.4
作者：
Claus Henn B;Schnaas L;Ettinger AS;Schwartz J;Lamadrid-Figueroa H;Hernández-Avila M;Amarasiriwardena C;Hu H;Bellinger DC;Wright RO;Téllez-Rojo MM
通讯作者：
Téllez-Rojo MM
影响因子：
5
作者：
ALLOTT, RW;KELLY, M;HEWITT, CN
通讯作者：
HEWITT, CN
DOI：
10.1007/s00244-010-9603-5
发表时间：
2011-08-01
影响因子：
4
作者：
Balabanova, Biljana;Stafilov, Trajce;Baceva, Katerina
通讯作者：
Baceva, Katerina
影响因子：
9.8
作者：
Al-Awadhi, Jasem M.;AlShuaibi, Arafat A.
通讯作者：
AlShuaibi, Arafat A.
影响因子：
11.4
作者：
Eastman, Rachel R.;Jursa, Tom P.;Benedetti, Chiara;Lucchini, Roberto G.;Smith, Donald R.
通讯作者：
Smith, Donald R.