A lower maximum bite force is a risk factor for developing cardiovascular disease: the Suita study.
A lower maximum bite force is a risk factor for developing cardiovascular disease: the Suita study.
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DOI：
10.1038/s41598-021-87252-5
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发表时间：
2021-04-07
影响因子：
4.6
通讯作者：
Miyamoto Y
中科院分区：
文献类型：
--
作者：
Hashimoto S;Kosaka T;Nakai M;Kida M;Fushida S;Kokubo Y;Watanabe M;Higashiyama A;Ikebe K;Ono T;Miyamoto Y
咀嚼功能的下降被认为与通过不适当的营养摄入而发生的心血管疾病（CVD）有关。本研究旨在探讨咀嚼功能的客观定量指标--最大咬合力（MBF）与脑血管病（中风和冠心病）的关系。受试者是1547名Suita研究的参与者，他们没有CVD病史，在2008年6月至2013年6月期间接受了医疗和牙科健康检查。除了在基线时进行基本的体格检查外，还测量了他们的MBF。他们随后接受了CVD发展的随访调查（平均随访时间为3.5年）。使用考克斯比例风险模型，通过多变量校正研究基线MBF与CVD发生之间的关系。随访期间，32例受试者发生CVD。趋势检验显示，在男性和女性相结合的模型中，基线MBF和CVD之间存在显著相关性。当按性别分析时，趋势检验发现基线MBF与女性CVD之间存在显著相关性。低MBF是反映咀嚼功能的客观定量指标，可能是CVD发生的危险因素。
Decreases in masticatory function are believed to be related to the development of cardiovascular disease (CVD) through inappropriate nutritional intake. This study focused on maximum bite force (MBF), which is an objective, quantitative index of masticatory function, and its association with the development of CVD (stroke and coronary heart disease) was investigated. The subjects were 1547 participants of the Suita study with no history of CVD who underwent medical and dental health examinations between June 2008 and June 2013. In addition to undergoing a basic physical examination at baseline, their MBF was measured. They subsequently underwent follow-up surveys for the development of CVD (mean follow-up, 3.5 years). The association between baseline MBF and the development of CVD was investigated by multivariate adjustment using a Cox proportional hazards model. CVD developed in 32 subjects during follow-up. The trend test showed a significant association between baseline MBF and CVD in a model that combined men and women. When analysed by sex, the trend test found a significant association between baseline MBF and CVD in women. Low MBF, which is an objective and quantitative index of masticatory function, may be a risk factor for the development of CVD.
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影响因子：
7.1
作者：
Steffen, LM;Jacobs, DR;Folsom, AR
通讯作者：
Folsom, AR
影响因子：
2.2
作者：
Seino, Yutaka;Nanjo, Kishio;Ueki, Kohjiro
通讯作者：
Ueki, Kohjiro
影响因子：
2.9
作者：
Matsui, Y;Ohno, K;Yamagata, K
通讯作者：
Yamagata, K
DOI：
10.1111/j.1600-0528.2009.00512.x
发表时间：
2010-02-01
影响因子：
2.3
作者：
Wakai, Kenji;Naito, Mariko;Kawamura, Takashi
通讯作者：
Kawamura, Takashi
影响因子：
8.3
作者：
Kokubo, Yoshihiro;Kamide, Kei;Kawano, Yuhei
通讯作者：
Kawano, Yuhei