Optimizing colorectal cancer screening by race and sex: Microsimulation analysis II to inform the American Cancer Society colorectal cancer screening guideline.
Optimizing colorectal cancer screening by race and sex: Microsimulation analysis II to inform the American Cancer Society colorectal cancer screening guideline.
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DOI：
10.1002/cncr.31542
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发表时间：
2018-07-15
期刊：
影响因子：
6.2
通讯作者：
Lansdorp-Vogelaar I
中科院分区：
文献类型：
--
作者：
Meester RGS;Peterse EFP;Knudsen AB;de Weerdt AC;Chen JC;Lietz AP;Dwyer A;Ahnen DJ;Siegel RL;Smith RA;Zauber AG;Lansdorp-Vogelaar I
结直肠癌（CRC）风险因种族和性别而异。这项研究是为2018年美国癌症协会CRC筛查指南提供信息的2项微观模拟分析之一，探讨了种族和性别对最佳CRC筛查策略的影响。两个癌症干预和监测模型网络的微观模拟模型，根据美国的发病率数据，用于评估各种筛查方法，开始和停止的年龄，以及4个人口统计学亚组的间隔（黑人和白色男性和女性）在40岁奥尔兹的预计终生CRC风险的2种情景下：1）假设风险自早期筛查时代以来一直保持稳定，2）假设风险与40岁以下观察到的发病趋势成比例增加。基于模型的筛选建议基于预测的获益水平（获得的生命年）和负担（所需的结肠镜检查次数）、增量负担-获益比以及与具有类似负担的策略相比的相对效率。当假设终生CRC风险随时间推移而稳定时，模型在白人开始筛查的推荐年龄（45岁与50岁）方面有所不同，但始终建议黑人从45岁开始筛查。当假设CRC风险增加时，模型建议从45岁开始，不考虑种族和性别。在这两种情况下推荐的策略包括每10年或15年进行一次结肠镜检查，每年进行一次粪便免疫化学检测，以及每5年进行一次计算机断层扫描结肠造影，直到75岁。微观模拟模型表明，CRC筛查应考虑从45岁的黑人和白人，如果终身风险已增加成比例的发病率为年轻的成年人。癌症2018;124：2974 - 85。版权所有© 2018作者.出版社：Wiley Periodicals，Inc.代表美国癌症协会一个已建立的建模方法表明，筛查应考虑从45岁的非裔美国人男性和女性，以及白色男性和女性，如果他们的结直肠癌的终身风险增加类似的趋势在年轻的年龄。第2964 - 73页
Colorectal cancer (CRC) risk varies by race and sex. This study, 1 of 2 microsimulation analyses to inform the 2018 American Cancer Society CRC screening guideline, explored the influence of race and sex on optimal CRC screening strategies. Two Cancer Intervention and Surveillance Modeling Network microsimulation models, informed by US incidence data, were used to evaluate a variety of screening methods, ages to start and stop, and intervals for 4 demographic subgroups (black and white males and females) under 2 scenarios for the projected lifetime CRC risk for 40‐year‐olds: 1) assuming that risk had remained stable since the early screening era and 2) assuming that risk had increased proportionally to observed incidence trends under the age of 40 years. Model‐based screening recommendations were based on the predicted level of benefit (life‐years gained) and burden (required number of colonoscopies), the incremental burden‐to‐benefit ratio, and the relative efficiency in comparison with strategies with similar burdens. When lifetime CRC risk was assumed to be stable over time, the models differed in the recommended age to start screening for whites (45 vs 50 years) but consistently recommended screening from the age of 45 years for blacks. When CRC risk was assumed to be increased, the models recommended starting at the age of 45 years, regardless of race and sex. Strategies recommended under both scenarios included colonoscopy every 10 or 15 years, annual fecal immunochemical testing, and computed tomographic colonography every 5 years through the age of 75 years. Microsimulation modeling suggests that CRC screening should be considered from the age of 45 years for blacks and for whites if the lifetime risk has increased proportionally to the incidence for younger adults. Cancer 2018;124:2974‐85. © 2018 The Authors. Cancer published by Wiley Periodicals, Inc. on behalf of American Cancer Society. An established modeling method suggests that screening should be considered from the age of 45 years for African American men and women, and for white men and women if their lifetime risk of colorectal cancer increases similarly to trends observed at younger ages. See also pages 2964‐73.
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影响因子：
--
作者：
Inadomi, John M.;Vijan, Sandeep;Janz, Nancy K.;Fagerlin, Angela;Thomas, Jennifer P.;Lin, Yunghui V.;Munoz, Roxana;Lau, Chim;Somsouk, Ma;El-Nachef, Najwa;Hayward, Rodney A.
通讯作者：
Hayward, Rodney A.
影响因子：
16.9
作者：
Bailey CE;Hu CY;You YN;Bednarski BK;Rodriguez-Bigas MA;Skibber JM;Cantor SB;Chang GJ
通讯作者：
Chang GJ
影响因子：
3.9
作者：
ARMINSKI, T. C.;McLEAN, D. W.
通讯作者：
McLEAN, D. W.
影响因子：
24.5
作者：
JASS, JR;YOUNG, PJ;ROBINSON, EM
通讯作者：
ROBINSON, EM
影响因子：
1.9
作者：
JOHANNSEN, LGK;MOMSEN, O;JACOBSEN, NO
通讯作者：
JACOBSEN, NO