Comparison of spoiled gradient echo and steady-state free-precession imaging for native myocardial T1 mapping using the slice-interleaved T1 mapping (STONE) sequence.
Comparison of spoiled gradient echo and steady-state free-precession imaging for native myocardial T1 mapping using the slice-interleaved T1 mapping (STONE) sequence.
复制标题
DOI：
10.1002/nbm.3598
复制
发表时间：
2016-10
影响因子：
2.9
通讯作者：
Nezafat R
中科院分区：
文献类型：
--
作者：
Jang J;Bellm S;Roujol S;Basha TA;Nezafat M;Kato S;Weingärtner S;Nezafat R
心脏 T1 标测可以对间质弥漫性纤维化进行非侵入性成像。心肌 T1 通常通过对反转脉冲后使用平衡稳态自由进动 (SSFP) 采集的图像进行体素拟合来计算。然而，SSFP 成像对 B1 和 B0 缺陷很敏感，这可能会导致额外的伪影。梯度回波 (GRE) 成像序列已用于心肌 T1 映射，但其使用仅限于较高的磁场，以补偿 GRE 与 SSFP 成像相比较低的信噪比 (SNR)。最近提出了具有 SSFP 读出 (STONE-SSFP) 的切片交错 T1 映射 (STONE) 序列用于本地心肌 T1 映射，它允许在每个反转脉冲后更长时间地恢复磁化 (>8 R-R)。在本研究中，我们假设更长的恢复时间可以实现更高的 SNR，并使用 STONE 和 1.5T 的 GRE 成像读数 (STONE-GRE) 实现本地心肌 T1 映射。通过数值模拟、体模和体内成像来比较 STONE-GRE 和 STONE-SSFP 在 1.5T 下进行原生心肌 T1 映射的性能。在数值模拟中，STONE-SSFP 显示出对 T2 和偏共振的敏感性。尽管 GRE 成像对 T2 不敏感，但由于反转脉冲性能对 T2 的依赖性，STONE-GRE 对 T2 仍然敏感。在模型研究中，与 STONE-SSFP 相比，STONE-GRE 的准确性、精密度和重复性相似。在体内研究中，STONE-GRE 和 STONE-SSFP 具有相似的心肌天然 T1 时间、精度、重复性和主观 T1 图质量。尽管与 SSFP 相比，GRE 成像读数的信噪比较低，但与 1.5T 的 STONE-SSFP 相比，STONE-GRE 提供了相似的原生心肌 T1 测量、精度、可重复性和主观图像质量。
Cardiac T1 mapping allows non-invasive imaging of interstitial diffuse fibrosis. Myocardial T1 is commonly calculated by voxel-wise fitting of the images acquired using balanced steady-state free precession (SSFP) after an inversion pulse. However, SSFP imaging is sensitive to B1 and B0 imperfection, which may result in additional artifacts. Gradient echo (GRE) imaging sequence has been used for myocardial T1 mapping, however its use has been limited to higher magnetic field to compensate for lower signal-to-noise ratio (SNR) of GRE vs. SSFP imaging. A slice-interleaved T1 mapping (STONE) sequence with SSFP readout (STONE-SSFP) has been recently proposed for native myocardial T1 mapping, which allows longer recovery of magnetization (>8 R-R) after each inversion pulse. In this study, we hypothesize that a longer recovery allows higher SNR and enables native myocardial T1 mapping using STONE with GRE imaging readout (STONE-GRE) at 1.5T. Numerical simulations, phantom and in-vivo imaging were performed to compare the performance of STONE-GRE and STONE-SSFP for native myocardial T1 mapping at 1.5T. In numerical simulations, STONE-SSFP shows sensitivity to both T2 and off-resonance. Despite insensitivity of GRE imaging to T2, STONE-GRE remains sensitive to T2 due to the dependence of the inversion pulse performance on T2. In the phantom study, STONE-GRE had inferior accuracy, precision, and similar repeatability as compared to STONE-SSFP. In in-vivo studies, STONE-GRE and STONE-SSFP had similar myocardial native T1 times, precision, repeatability and subjective T1 map quality. Despite lower SNR of GRE imaging readout compared to SSFP, STONE-GRE provides similar native myocardial T1 measurements, precision, repeatability and subjective image quality when compared to STONE-SSFP at 1.5T.
登录
查看更多内容
影响因子：
37.8
作者：
Cerqueira, MD;Weissman, NJ;Verani, MS
通讯作者：
Verani, MS
影响因子：
3.3
作者：
WANG, Y;RIEDERER, SJ;EHMAN, RL
通讯作者：
EHMAN, RL
影响因子：
24
作者：
Mewton, Nathan;Liu, Chia Ying;Croisille, Pierre;Bluemke, David;Lima, Joao A. C.
通讯作者：
Lima, Joao A. C.
DOI：
10.1186/1532-429x-14-63
发表时间：
2012-09-10
期刊：
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
影响因子：
--
作者：
Kellman P;Wilson JR;Xue H;Ugander M;Arai AE
通讯作者：
Arai AE
影响因子：
3.3
作者：
Akcakaya, Mehmet;Basha, Tamer A.;Weingaertner, Sebastian;Roujol, Sebastien;Berg, Sophie;Nezafat, Reza
通讯作者：
Nezafat, Reza