Assessment of myocardial fibrosis with cardiovascular magnetic resonance.

Assessment of myocardial fibrosis with cardiovascular magnetic resonance.
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DOI:
10.1016/j.jacc.2010.11.013
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发表时间:
2011-02-22
影响因子:
24
通讯作者:
Lima, Joao A. C.
Lima, Joao A. C.
中科院分区:
医学1区
文献类型:
--
作者:
Mewton, Nathan;Liu, Chia Ying;Croisille, Pierre;Bluemke, David;Lima, Joao A. C.

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弥漫性间质性或替代性心肌纤维化是多种心肌病的共同特征。心肌纤维化导致心脏舒张和收缩功能受损,并与不良心血管事件相关。心脏磁共振(CMR)可以独特地表征替代纤维化的程度,并可能在各种心肌病的预后价值。心肌T1标测是一种新兴的技术,可以提高CMR的诊断准确性,特别是对间质弥漫性心肌纤维化。因此,CMR可以整合到大量患者的监测和治疗管理中。本文就CMR在心肌纤维化评价中的优势和局限性作一综述。
Diffuse interstitial or replacement myocardial fibrosis are common features of a broad variety of cardiomyopathies. Myocardial fibrosis leads to impaired cardiac diastolic and systolic function and is related to adverse cardiovascular events. Cardiac magnetic resonance (CMR) may uniquely characterize the extent of replacement fibrosis and may have prognostic value in various cardiomyopathies. Myocardial T1 mapping is an emerging technique that could improve CMR’s diagnostic accuracy especially for interstitial diffuse myocardial fibrosis. As such, CMR could be integrated in the monitoring and the therapeutic management of a large number of patients. This review summarizes the advantages and limitations of CMR for the assessment of myocardial fibrosis.
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