The Chlamydomonas genome project: a decade on.
The Chlamydomonas genome project: a decade on.
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DOI:
10.1016/j.tplants.2014.05.008
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发表时间:
2014-10
影响因子:
20.5
通讯作者:
Prochnik, Simon
中科院分区:
文献类型:
--
作者:
Blaby, Ian K.;Blaby-Haas, Crysten E.;Tourasse, Nicolas;Hom, Erik F. Y.;Lopez, David;Aksoy, Munevver;Grossman, Arthur;Umen, James;Dutcher, Susan;Porter, Mary;King, Stephen;Witman, George B.;Stanke, Mario;Harris, Elizabeth H.;Goodstein, David;Grimwood, Jane;Schmutz, Jeremy;Vallon, Olivier;Merchant, Sabeeha S.;Prochnik, Simon
The green alga Chlamydomonas reinhardtii is a popular unicellular organism for studying photosynthesis, cilia biogenesis and micronutrient homeostasis. Ten years since its genome project was initiated, an iterative process of improvements to the genome and gene predictions has propelled this organism to the forefront of the “omics” era. Housed at Phytozome, the Joint Genome Institute’s (JGI) plant genomics portal, the most up-to-date genomic data include a genome arranged on chromosomes and high-quality gene models with alternative splice forms supported by an abundance of RNA-Seq data. Here, we present the past, present and future of Chlamydomonas genomics. Specifically, we detail progress on genome assembly and gene model refinement, discuss resources for gene annotations, functional predictions and locus ID mapping between versions and, importantly, outline a standardized framework for naming genes.
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