Repetitive nociceptive stimulation elicits complex behavioral changes in Hirudo: evidence of arousal and motivational adaptations.
Repetitive nociceptive stimulation elicits complex behavioral changes in Hirudo: evidence of arousal and motivational adaptations.
复制标题
DOI：
10.1242/jeb.245895
复制
发表时间：
2023-08-15
期刊：
影响因子：
--
通讯作者：
中科院分区：
文献类型：
--
作者：
Appropriate responses to real or potential damaging stimuli to the body (nociception) are critical to an animal's short- and long-term survival. The initial goal of this study was to examine habituation of withdrawal reflexes (whole-body and local shortening) to repeated mechanical nociceptive stimuli (needle pokes) in the medicinal leech, Hirudo verbana, and assess whether injury altered habituation to these nociceptive stimuli. While repeated needle pokes did reduce shortening in H. verbana, a second set of behavior changes was observed. Specifically, animals began to evade subsequent stimuli by either hiding their posterior sucker underneath adjacent body segments or engaging in locomotion (crawling). Animals differed in terms of how quickly they adopted evasion behaviors during repeated stimulation, exhibiting a multi-modal distribution for early, intermediate and late evaders. Prior injury had a profound effect on this transition, decreasing the time frame in which animals began to carry out evasion and increasing the magnitude of these evasion behaviors (more locomotory evasion). The data indicate the presence in Hirudo of a complex and adaptive defensive arousal process to avoid noxious stimuli that is influenced by differences in internal states, prior experience with injury of the stimulated areas, and possibly learning-based processes. Repeated noxious stimulation of the medicinal leech elicits a transition from reflexive withdrawal to pre-emptive evasion behaviors that is modifiable as a result of differences in internal state or prior injury.
登录
查看更多内容
影响因子：
3.7
作者：
Paulsen RT;Burrell BD
通讯作者：
Burrell BD
影响因子：
16.2
作者：
Baca, Serapio M.;Marin-Burgin, Antonia;Kristan, William B., Jr.
通讯作者：
Kristan, William B., Jr.
影响因子：
64.5
作者：
Anderson DJ;Adolphs R
通讯作者：
Adolphs R
DOI：
10.1242/jeb.243404
发表时间：
2022-06-01
期刊：
The Journal of experimental biology
影响因子：
--
作者：
通讯作者：
--
影响因子：
9.2
作者：
Crook, Robyn J.;Dickson, Katharine;Walters, Edgar T.
通讯作者：
Walters, Edgar T.