Prospective risk factors for traumatic event reexposure in community syringe exchange participants.
Prospective risk factors for traumatic event reexposure in community syringe exchange participants.
复制标题
社区注射器交换参与者再次暴露创伤事件的前瞻性危险因素。
DOI：
10.1016/j.drugalcdep.2014.02.010
复制
发表时间：
2014-05-01
影响因子：
4.2
通讯作者：
Kidorf, Michael S.
中科院分区：
文献类型：
--
作者：
Peirce, Jessica M.;Schacht, Rebecca L.;Brooner, Robert K.;King, Van L.;Kidorf, Michael S.
注射吸毒者创伤事件再暴露与吸毒增加和精神症状的可能性有关。这是第一项研究，以检查固定的和随时间变化的因素，是前瞻性地与新的创伤性事件的注射吸毒者重新暴露。在注射器交换计划中登记的注射吸毒者参加了一项为期16个月的家长研究，比较增加药物滥用治疗登记的策略。参与者（N = 162）完成了人口统计学、精神病治疗史和终生创伤事件暴露的基线测量。每月随访评估上个月创伤事件暴露，海洛因和可卡因使用天数，犯罪活动和药物滥用治疗参与。广义估计方程模型测试了固定基线和随时间变化的因素对创伤事件再暴露在同一个月，下一个月，两个月后的影响。创伤性事件再暴露的重要固定风险因素包括女性和既往精神病治疗。此外，每一个过去的创伤事件暴露与再暴露的可能性增加。在考虑了所有其他因素后，每天使用可卡因与创伤事件再暴露的风险增加有关，但这种风险很小，但持续增加。在前一个月再次暴露于创伤事件的风险增加了一倍以上。注射吸毒者经历的模式是，吸毒与随后创伤事件再暴露的风险增加有关，创伤事件再暴露与进一步吸毒和持续再暴露有关。提出了解决这些问题的影响注射毒品使用者。
Traumatic event reexposure in injecting drug users is associated with increased drug use and potential for psychiatric symptoms. This is the first study to examine fixed and time-varying factors that are prospectively associated with new traumatic event reexposure in injecting drug users. Injecting drug users registered in a syringe exchange program were enrolled in a 16-month parent study comparing strategies to increase drug abuse treatment enrollment. Participants (N = 162) completed baseline measures of demographics, psychiatric treatment history, and lifetime traumatic event exposure. Monthly follow-ups assessed past-month traumatic event exposure, days of heroin and cocaine use, criminal activity, and drug abuse treatment participation. Generalized Estimating Equations models tested the influence of fixed baseline and time-varying factors on traumatic event reexposure in the same month, the following month, and two months later. Significant fixed risk factors for traumatic event reexposure include female gender and past psychiatric treatment. In addition, each past traumatic event exposure was associated with an increased likelihood of reexposure. After accounting for all other factors, each day of cocaine use was associated with a small but persistent increased risk of traumatic event reexposure. Reexposure to a traumatic event in the prior month more than doubled the risk of subsequent reexposure. Injecting drug users experience a pattern in which drug use is associated with increased risk of subsequent traumatic event reexposure, and traumatic event reexposure is associated with further drug use and continued reexposure. Implications for addressing these concerns in injecting drug users are presented.
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影响因子：
3.4
作者：
Gilbert, Louisa;El-Bassel, Nabila;Chang, Mingway;Wu, Elwin;Roy, Lolita
通讯作者：
Roy, Lolita
影响因子：
4.2
作者：
Epstein-Ngo, Quyen M.;Cunningham, Rebecca M.;Walton, Maureen A.
通讯作者：
Walton, Maureen A.
DOI：
10.1007/s11524-011-9619-9
发表时间：
2012-02-01
影响因子：
6.6
作者：
Peirce, Jessica M.;Kolodner, Ken;Kidorf, Michael S.
通讯作者：
Kidorf, Michael S.
DOI：
10.1093/jurban/jth138
发表时间：
2004-12-01
影响因子：
6.6
作者：
Breslau, N;Wilcox, HC;Anthony, JC
通讯作者：
Anthony, JC
影响因子：
3.6
作者：
Kubany, ES;Haynes, SN;Burns, K
通讯作者：
Burns, K