The neurocognitive effects of a past cannabis use disorder in a diverse sample of people living with HIV.

The neurocognitive effects of a past cannabis use disorder in a diverse sample of people living with HIV.
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DOI:
10.1080/09540121.2020.1822504
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发表时间:
2021-11
影响因子:
1.7
通讯作者:
Mindt, Monica Rivera
Mindt, Monica Rivera
中科院分区:
医学4区
文献类型:
--
作者:
Crook, Cara L.;Savin, Micah J.;Byrd, Desiree;Summers, Angela C.;Guzman, Vanessa A.;Morris, Emily P.;Tureson, Kayla;Aghvinian, Maral;Cham, Heining;Mindt, Monica Rivera

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People living with HIV (PLWH) report higher rates of cannabis use than the general population, a trend likely to continue in light of recent policy changes and the reported therapeutic benefits of cannabis for PLWH. Therefore, it is important to better understand cannabis-associated effects on neurocognition, especially as PLWH are at heightened risk for neurocognitive impairment. This study aimed to elucidate the effects of a past cannabis use disorder on current neurocognition in a diverse sample of PLWH. This cross-sectional study included 138 PLWH (age M(SD) = 47.28(8.06); education M(SD) = 12.64(2.73); 73% Male; 71% Latinx) who underwent neuropsychological, DSM-diagnostic, and urine toxicology evaluations. One-way ANCOVAs were conducted to examine effects of a past cannabis use disorder (CUD+) on tests of attention/working memory, processing speed, executive functioning, verbal fluency, learning, memory, and motor ability. Compared to the past CUD- group, the past CUD+ group performed significantly better on tests of processing speed, visual learning and memory, and motor ability (p’s < .05). Findings suggest PLWH with past cannabis use have similar or better neurocognition across domains compared to PLWH without past use.
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发表时间: 2011-10-01
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