Blood markers of alcoholic liver disease.
Blood markers of alcoholic liver disease.
复制标题
酒精性肝病的血液标志物。
DOI:
10.1007/978-1-4615-7718-8_20
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发表时间:
1988
期刊:
影响因子:
--
通讯作者:
Lieber,CS
中科院分区:
文献类型:
--
作者:
Lieber,CS
Not all heavy drinkers develop severe alcoholic liver disease. Genetic factors are probably involved, but no corresponding useful markers have been developed thus far. Of greater practical applicability is the recognition of early changes in the liver that may indicate that the process of scarring or fibrosis has been initiated. Measurement of breakdown products of collagen, the protein of the fibrotic tissue, have been found to be useful for detecting these early stages. Assessment of glutamic dehydrogenase activity in the serum also provides some indication of the degree of inflammation and necrosis present in the liver, but not of the alcohol intake. The severity of the latter can be assessed with a variety of biological markers, to which circulating antibodies against acetaldehyde adducts have recently been added.
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影响因子:
--
作者:
B. Tait;I. Mackay
通讯作者:
I. Mackay
影响因子:
29.4
作者:
P. Teychenné;E. Jones;K. Ishak;D. Calne
通讯作者:
D. Calne
DOI:
10.1016/0002-9343(78)90688-5
发表时间:
1978
期刊:
The American journal of medicine
影响因子:
--
作者:
W. Schlippert;S. Anuras
通讯作者:
S. Anuras
DOI:
10.1111/j.0954-6820.1979.tb00775.x
发表时间:
2009
期刊:
Acta medica Scandinavica. Supplementum
影响因子:
--
作者:
R. Olsson
通讯作者:
R. Olsson
影响因子:
--
作者:
L. Swank;G. Chejfec;B. Nemchausky
通讯作者:
B. Nemchausky