A Systematic Review of Epidemiology and Risk Factors Associated With Chinese Inflammatory Bowel Disease.
A Systematic Review of Epidemiology and Risk Factors Associated With Chinese Inflammatory Bowel Disease.
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DOI：
10.3389/fmed.2018.00183
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发表时间：
2018
影响因子：
3.9
通讯作者：
Yuan A
中科院分区：
文献类型：
--
作者：
Cui G;Yuan A
背景资料：最近的流行病学数据显示，在中国大陆，一个快速发展的工业化地区，在过去的二十年中，炎症性肠病（IBD）的患病率和发病率急剧上升。目的：我们进行了一项系统评价，以调查中国大陆IBD发病率的变化趋势，并总结了与中国IBD相关的危险因素的最新研究结果。研究方法：通过MEDLINE和EMBASE（英文文献）、中国学术期刊全文数据库（CJFD）和万方数据库中的中国科学期刊数据库（CSPD）（中文文献）的电子数据库检索获得相关参考文献。结果：共收集到中文摘要1,584篇，英文摘要171篇。最终确定8篇中文流行病学资料全文，25篇中文危险因素资料全文，7篇英文流行病学资料全文，12篇英文危险因素资料全文，并纳入分析。纳入的流行病学研究数据显示，随着时间的推移，IBD在中国大陆的发病率显著增加，目前IBD、UC和CD的发病率分别为1.80/1，000，000（IBD）、1.33/1，000，000（UC）和0.46/1，000，000（CD），但不同地区和少数民族人群的发病率不同。此外，据报道，包括环境因素、饮食、肠道感染因子、卫生、压力和生活方式在内的几个风险因素与中国IBD的发病率增加有关。结论：本系统评价显示中国大陆IBD的发病率增加。尽管仍低于西方国家，但中国人口众多，因此IBD患者总数可能并不像以前认为的那么少，中国IBD的疾病负担可能被低估。最近的流行病学数据显示，在中国大陆，一个快速发展的工业化地区，在过去的二十年中，炎症性肠病（IBD）的患病率和发病率急剧上升。本系统综述基于近期流行病学数据，显示中国大陆IBD发病率显著增加，但不同地区和少数民族人群的发病率存在差异。据报道，IBD的几个潜在危险因素，包括环境因素、饮食、肠道感染因子、卫生、压力和生活方式，与中国IBD的发病率增加有关。本系统回顾了中国IBD的流行病学和危险因素研究，扩大了对中国IBD的发生、分布、地理差异和危险因素的了解，并将为临床医生了解中国大陆IBD的现状提供重要信息。亮点
Background: Recent epidemiological data have revealed a dramatically rising prevalence and incidence of inflammatory bowel diseases (IBDs) in Mainland China, a rapidly growing industrialized region, over the last two decades. Objectives: We performed a systematic review to investigate the changing trends in the incidence of IBD in Mainland China and summarized the recent findings in risk factors associated with Chinese IBD. Methods: Relevant references were obtained from an electronic database search via MEDLINE and EMBASE (for English literatures), the China Academic Journals Full-text Database (CJFD) and the China Science Periodical Database (CSPD) in Wanfang Data (for Chinese literatures). Results: Total 1,584 abstracts in Chinese and 171 abstracts in English were collected. Eight full-text with epidemiological data, 25 with risk factor data in Chinese and 7 full-text with epidemiological data, 12 with risk factor data in English were finally identified and included for analysis. Data from included epidemiological studies has showed a striking increase in the incidence rate of IBD in Mainland China over time, and current incidence rates for IBD, UC, and CD were 1.80 (IBD), 1.33 (UC), and 0.46/1,000,000 (CD), though it varies among regions and ethnic minority populations. In addition, several risk factors including environmental factors, diet, intestinal infectious agents, hygiene, stress, and lifestyle have been reported to be associated with the increased incidence of Chinese IBD. Conclusion: This systematic review revealed an increased incidence of IBD in Mainland China. Although it is still lower than that in the Western world, however, China has a huge population; therefore, the total number of IBD patients might not be so little as previously thought and the disease burden of IBD in China is likely underestimated. Recent epidemiological data have revealed a dramatically rising prevalence and incidence of inflammatory bowel diseases (IBD) in Mainland China, a rapidly growing industrialized region, over the last two decades. This systematic review based on recent epidemiological data has revealed a striking increase in the incidence rate of IBD in Mainland China, though it varies among regions and ethnic minority populations. Several potential risk factors of IBD including environmental factors, diet, intestinal infectious agents, hygiene, stress, and lifestyle have been reported to be associated with the increased incidence of Chinese IBD. This systematic review on epidemiologic and risk factor studies has expanded understanding of the occurrence, distribution, geographic variance and risk factors of Chinese IBD and will provide clinicians important information in understanding current status of IBD in Mainland China. HIGHLIGHTS
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影响因子：
29.4
作者：
Ng, Siew C.;Tang, Whitney;Chan, Francis K. L.
通讯作者：
Chan, Francis K. L.
中国人群炎症性肠病的疾病负担和临床特征：系统评价和荟萃分析
DOI：
10.3390/ijerph14030238
发表时间：
2017-02-28
影响因子：
--
作者：
Li X;Song P;Li J;Tao Y;Li G;Li X;Yu Z
通讯作者：
Yu Z
影响因子：
30.8
作者：
通讯作者：
--
影响因子：
7.6
作者：
Coughlan, A.;Wylde, R.;Hussey, S.
通讯作者：
Hussey, S.
影响因子：
24.5
作者：
Bernstein, Charles N.;Shanahan, Fergus
通讯作者：
Shanahan, Fergus