The ageing cortical synapse: hallmarks and implications for cognitive decline.

The ageing cortical synapse: hallmarks and implications for cognitive decline.
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DOI:
10.1038/nrn3200
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发表时间:
2012-03-07
影响因子:
34.7
通讯作者:
Baxter, Mark G.
Baxter, Mark G.
中科院分区:
医学1区
文献类型:
--
作者:
Morrison, John H.;Baxter, Mark G.

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Normal aging is associated with impairments in cognitive function, including memory, and with specific and relatively subtle synaptic alterations in the hippocampus and prefrontal cortex. The authors describe these structural changes reported in monkeys and rodents, how they might affect age-associated cognitive decline and potential strategies to limit their impact.
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