Daytime napping and the risk of all-cause and cause-specific mortality: a 13-year follow-up of a British population.
Daytime napping and the risk of all-cause and cause-specific mortality: a 13-year follow-up of a British population.
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DOI：
10.1093/aje/kwu036
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发表时间：
2014-05-01
影响因子：
5
通讯作者：
Khaw KT
中科院分区：
文献类型：
--
作者：
Leng Y;Wainwright NW;Cappuccio FP;Surtees PG;Hayat S;Luben R;Brayne C;Khaw KT
流行病学研究报告了关于白天小睡与死亡风险之间关系的相互矛盾的结果，而且在英国人口中几乎没有关于潜在关联的数据。我们在欧洲癌症前瞻性调查诺福克研究中调查了白天午睡与全因或特定原因死亡率之间的关系，这是一项基于英国人群的队列研究。在1998年至2000年期间，16374名男性和女性回答了有关午睡习惯的问题，在13年的随访中，共有3251人死亡。白天午睡与全因死亡风险增加相关(平均每天午睡少于1小时，风险比= 1.14,95%可信区间：1.02,1.27；对于平均每天午睡1小时或更长时间，风险比= 1.32,95%可信区间：1.04,1.68)，与年龄、性别、社会阶层、教育水平、婚姻状况、就业状况、体重指数、体育活动水平、吸烟状况、酒精摄入量、抑郁症、自我报告的一般健康状况、使用催眠药物或其他药物、夜间卧床时间和是否存在既往健康状况无关。这种关联在呼吸系统疾病死亡（午睡少于1小时，风险比= 1.40,95%可信区间：0.95,2.05；午睡1小时或以上，风险比= 2.56,95%可信区间：1.34,4.86）和65岁或65岁以下的个体中更为明显。白天小睡过多可能是潜在健康风险的一个有用标志，尤其是呼吸系统问题，尤其是65岁或65岁以下的人。需要进一步的研究来澄清所观察到的关联的性质。
Epidemiologic studies have reported conflicting results on the relationship between daytime napping and mortality risk, and there are few data on the potential association in the British population. We investigated the associations between daytime napping and all-cause or cause-specific mortality in the European Prospective Investigation Into Cancer-Norfolk study, a British population-based cohort study. Among the 16,374 men and women who answered questions on napping habits between 1998 and 2000, a total of 3,251 died during the 13-year follow-up. Daytime napping was associated with an increased risk of all-cause mortality (for napping less than 1 hour per day on average, hazard ratio = 1.14, 95% confidence interval: 1.02, 1.27; for napping 1 hour or longer per day on average, hazard ratio = 1.32, 95% confidence interval: 1.04, 1.68), independent of age, sex, social class, educational level, marital status, employment status, body mass index, physical activity level, smoking status, alcohol intake, depression, self-reported general health, use of hypnotic drugs or other medications, time spent in bed at night, and presence of preexisting health conditions. This association was more pronounced for death from respiratory diseases (for napping less than 1 hour, hazard ratio = 1.40, 95% confidence interval: 0.95, 2.05; for napping 1 hour or more, hazard ratio = 2.56, 95% confidence interval: 1.34, 4.86) and in individuals 65 years of age or younger. Excessive daytime napping might be a useful marker of underlying health risk, particularly of respiratory problems, especially among those 65 years of age or younger. Further research is required to clarify the nature of the observed association.
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