The Protein Ontology: a structured representation of protein forms and complexes.

The Protein Ontology: a structured representation of protein forms and complexes.
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DOI:
10.1093/nar/gkq907
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发表时间:
2011-01
影响因子:
14.9
通讯作者:
Wu CH
Wu CH
中科院分区:
生物学2区
文献类型:
--
作者:
Natale DA;Arighi CN;Barker WC;Blake JA;Bult CJ;Caudy M;Drabkin HJ;D'Eustachio P;Evsikov AV;Huang H;Nchoutmboube J;Roberts NV;Smith B;Zhang J;Wu CH

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蛋白质本体 (PRO) 提供了特定蛋白质类别的正式的、基于逻辑的分类,包括蛋白质亚型、变体和修饰形式的结构化表示。 PRO 最初专注于人类、小鼠和大肠杆菌中发现的蛋白质,现在包括蛋白质复合物的代表。 PRO 联盟与其他生物医学本体论和蛋白质知识库的开发人员合作,提供正式组织和整合精确蛋白质形式表示的能力,从而提高蛋白质研究结果的可访问性。 PRO (http://pir.georgetown.edu/pro) 是开放生物医学本体铸造厂的一部分。
The Protein Ontology (PRO) provides a formal, logically-based classification of specific protein classes including structured representations of protein isoforms, variants and modified forms. Initially focused on proteins found in human, mouse and Escherichia coli, PRO now includes representations of protein complexes. The PRO Consortium works in concert with the developers of other biomedical ontologies and protein knowledge bases to provide the ability to formally organize and integrate representations of precise protein forms so as to enhance accessibility to results of protein research. PRO (http://pir.georgetown.edu/pro) is part of the Open Biomedical Ontology Foundry.
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