Magnetic resonance elastography: a review.
Magnetic resonance elastography: a review.
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DOI：
10.1002/ca.21006
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发表时间：
2010-07
期刊：
影响因子：
2.4
通讯作者：
Ehman, Richard L.
中科院分区：
文献类型：
--
作者：
Mariappan, Yogesh K.;Glaser, Kevin J.;Ehman, Richard L.
在组织中产生剪切波，采集描绘所诱发的剪切波的传播的MR图像，并处理剪切波的图像以产生组织硬度的定量图，称为弹性图。磁共振弹性成像（MRE）是一种快速发展的定量评估组织力学性能的技术。该技术可以被认为是一种基于成像的触诊对应物，通常被医生用于诊断和表征疾病。触诊作为一种诊断方法的成功是基于这样一个事实，即组织的机械性能往往受到疾病过程（如癌症、炎症和纤维化）的影响。MRE通过使用特殊的磁共振成像（MRI）技术评估机械波通过组织的传播来获得有关组织刚度的信息。该技术主要包括三个步骤： MRE已经在临床上用于评估慢性肝病患者，并正在成为肝活检的安全，可靠和非侵入性替代方案，用于肝纤维化分期。还在研究地雷危险教育在其他器官病理学方面的应用，包括脑、乳房、血管、心脏、肾脏、肺和骨骼肌。这篇综述文章的目的是向临床解剖学家介绍这项技术，并总结目前正在追求的一些临床应用。
generating shear waves in the tissue, acquiring MR images depicting the propagation of the induced shear waves and processing the images of the shear waves to generate quantitative maps of tissue stiffness, called elastograms. Magnetic Resonance Elastography (MRE) is a rapidly developing technology for quantitatively assessing the mechanical properties of tissue. The technology can be considered to be an imaging-based counterpart to palpation, commonly used by physicians to diagnose and characterize diseases. The success of palpation as a diagnostic method is based on the fact that the mechanical properties of tissues are often dramatically affected by the presence of disease processes such as cancer, inflammation, and fibrosis. MRE obtains information about the stiffness of tissue by assessing the propagation of mechanical waves through the tissue with a special magnetic resonance imaging (MRI) technique. The technique essentially involves three steps: MRE is already being used clinically for the assessment of patients with chronic liver diseases and is emerging as a safe, reliable and noninvasive alternative to liver biopsy for staging hepatic fibrosis. MRE is also being investigated for application to pathologies of other organs including the brain, breast, blood vessels, heart, kidneys, lungs and skeletal muscle. The purpose of this review article is to introduce this technology to clinical anatomists and to summarize some of the current clinical applications that are being pursued.
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影响因子：
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