Surgical Management of Gastroesophageal Reflux Disease in Obesity

Surgical Management of Gastroesophageal Reflux Disease in Obesity
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肥胖症胃食管反流病的手术治疗

DOI:
10.1007/s10620-008-0415-7
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发表时间:
2008
影响因子:
3.1
通讯作者:
S. Ikramuddin
S. Ikramuddin
中科院分区:
医学3区
文献类型:
--
作者:
S. Ikramuddin

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减肥手术在今天是无处不在的。在患有胃食管反流病(GERD)的肥胖患者中,它越来越多地被用作胃底折叠术的替代方法,因为它不仅对GERD有影响,而且对其他共病也有影响。传统的GERD手术旨在增强对抗反流的机械屏障,减少胃酸产生,改善胃排空或将胆汁从胃中转移。Roux-en-Y胃旁路术除了导致患者体重显著减轻外,还解决了这些问题。带状可能对患者的GERD有积极的影响,尽管程度较小。十二指肠转位术为碱性反流患者提供了极好的控制。1991年美国国立卫生研究院关于确定减肥手术候选人的指南的修订已经过期,考虑扩大体重指数和合并症要求以反映这些技术为GERD患者提供的益处可能是可行的。
Bariatric surgery is ubiquitous today. In the obese patient with comorbid gastroesophageal reflux disease (GERD), it is increasingly being used as an alternative to fundoplication because it not only has an effect on GERD but also on other comorbid illnesses. Traditional GERD surgery is designed to augment the mechanical barriers against reflux, decrease acid production in the stomach, improve gastric emptying, or divert bile from the stomach. Roux-en-Y gastric bypass addresses these issues in addition to resulting in profound weight loss in patients. Banding may have a positive influence in patients’ GERD, though to a lesser extent. The duodenal switch provides excellent control for patients with alkaline reflux. A revision of the 1991 National Institutes of Health guidelines for determining bariatric surgical candidates is overdue, and it may be feasible to consider expanding the body mass index and comorbidity requirements to reflect the benefits offered by these techniques for GERD patients.
DOI: 10.1056/nejmoa066603
发表时间: 2007-08-23
影响因子: 158.5
作者:
Adams, Ted D.;Gress, Richard E.;Hunt, Steven C.
通讯作者: Hunt, Steven C.
DOI: 10.1056/nejmoa012908
发表时间: 2002-05-23
影响因子: 158.5
作者:
Cummings, DE;Weigle, DS;Purnell, JQ
通讯作者: Purnell, JQ
DOI: 10.1093/ajcn/83.2.461s
发表时间: 2006-02-01
影响因子: 7.1
作者:
Martin, ASG;Obin, MS
通讯作者: Obin, MS