Evolutionary history and stress regulation of the lectin superfamily in higher plants.
Evolutionary history and stress regulation of the lectin superfamily in higher plants.
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DOI：
10.1186/1471-2148-10-79
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发表时间：
2010-03-18
影响因子：
3.4
通讯作者：
Ramachandran S
中科院分区：
文献类型：
--
作者：
Jiang SY;Ma Z;Ramachandran S
凝集素是一类碳水化合物结合蛋白。它们在各种生物过程中发挥作用。然而，人们对它们的进化历史及其在植物逆境调节中的功能知之甚少。来自不同植物物种的全基因组序列的可用性使得进行全基因组探索以进一步了解其生物学功能成为可能。高等植物基因组编码大量凝集素蛋白。基于它们的域结构和系统发育分析，提出了一个新的分类系统。在这个系统中，12 个不同的家族被分类，其中四个家族由最近鉴定的植物凝集素成员组成。进一步的分析表明，一些凝集素家族表现出物种特异性扩张和快速的生死进化。串联和片段复制被认为是驱动凝集素扩增的主要机制，尽管逆基因也对大豆和水稻中新凝集素基因的诞生做出了重大贡献。有证据表明，凝集素基因参与生物/非生物胁迫调节，串联/片段复制可能被视为植物通过复制和表达分歧来适应各种环境胁迫的驱动因素。该基因超家族的每个成员都可能在特定的胁迫条件下发挥专门的作用，并作为各种环境因素（例如寒冷、干旱、高盐度以及生物胁迫）的调节器。我们的研究提供了植物凝集素基因超家族的新轮廓，并促进了对植物凝集素基因在谱系特异性扩展中及其在生物/非生物胁迫相关发育过程中的功能的理解。
Lectins are a class of carbohydrate-binding proteins. They play roles in various biological processes. However, little is known about their evolutionary history and their functions in plant stress regulation. The availability of full genome sequences from various plant species makes it possible to perform a whole-genome exploration for further understanding their biological functions. Higher plant genomes encode large numbers of lectin proteins. Based on their domain structures and phylogenetic analyses, a new classification system has been proposed. In this system, 12 different families have been classified and four of them consist of recently identified plant lectin members. Further analyses show that some of lectin families exhibit species-specific expansion and rapid birth-and-death evolution. Tandem and segmental duplications have been regarded as the major mechanisms to drive lectin expansion although retrogenes also significantly contributed to the birth of new lectin genes in soybean and rice. Evidence shows that lectin genes have been involved in biotic/abiotic stress regulations and tandem/segmental duplications may be regarded as drivers for plants to adapt various environmental stresses through duplication followed by expression divergence. Each member of this gene superfamily may play specialized roles in a specific stress condition and function as a regulator of various environmental factors such as cold, drought and high salinity as well as biotic stresses. Our studies provide a new outline of the plant lectin gene superfamily and advance the understanding of plant lectin genes in lineage-specific expansion and their functions in biotic/abiotic stress-related developmental processes.
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影响因子：
7
作者：
Blanc, G;Hokamp, K;Wolfe, KH
通讯作者：
Wolfe, KH
影响因子：
3.1
作者：
Birch, ANE;Geoghegan, IE;Gatehouse, JA
通讯作者：
Gatehouse, JA
Pfam：氏族、网络工具和服务。
影响因子：
14.9
作者：
Finn, Robert D.;Mistry, Jaina;Schuster-Bockler, Benjamin;Griffiths-Jones, Sam;Hollich, Volker;Lassmann, Timo;Moxon, Simon;Marshall, Mhairi;Khanna, Ajay;Durbin, Richard;Eddy, Sean R.;Sonnhammer, Erik L. L.;Bateman, Alex
通讯作者：
Bateman, Alex
影响因子：
2
作者：
Baker, R. L.;Brown, R. L.;Fakhoury, A. M.
通讯作者：
Fakhoury, A. M.
影响因子：
3
作者：
Bell, HA;Fitches, EC;Gatehouse, AMR
通讯作者：
Gatehouse, AMR