Continued drug use during methadone treatment in China: a retrospective analysis of 19,026 service users.
Continued drug use during methadone treatment in China: a retrospective analysis of 19,026 service users.
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DOI：
10.1016/j.jsat.2013.12.004
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发表时间：
2014-07
影响因子：
3.9
通讯作者：
National Methadone Maintenance Treatment Working Group
中科院分区：
文献类型：
--
作者：
Sullivan SG;Wu Z;Cao X;Liu E;Detels R;National Methadone Maintenance Treatment Working Group
本研究检查了中国全国范围内的数据，以评估客户接受 6 个月美沙酮治疗后的结果。对 2008 年 4 月至 2010 年 3 月期间登记的 19,026 名客户的数据进行了审查，了解艾滋病毒危险行为的变化和新艾滋病毒病例的出现。使用多变量逻辑回归来确定 MMT 期间与非法药物使用相关的因素。客户报告称，吸毒和相关危险行为减少，社会功能得到改善。新增艾滋病病毒感染者24例。持续吸毒与出勤率低（OR = 5.98，95% CI = 4.69–7.63）、经常见到吸毒的朋友（OR = 3.72（每天与从不），95% CI = 3.18-4.34）以及家庭关系困难（OR = 2.03，困难与良好，95% CI = 1.63-2.52）有关。美沙酮剂量与治疗期间继续吸毒无关。中国的 MMT 项目似乎对那些仍在接受治疗的客户产生了积极影响，但需要探索增加可及性的策略。
This study examined nation-wide data from China to assess client outcomes after 6-months of methadone treatment. Data on 19,026 clients enrolled between April 2008 and March 2010 were reviewed for changes in HIV-risk behaviours and emergence of new HIV cases. Multivariable logistic regression was used to identify factors associated with illicit drug use while in MMT. Clients reported reduced drug use and related risk behaviours and improved social functioning. There were 24 newly-identified cases of HIV. Continued drug use was associated with low attendance (OR = 5.98, 95% CI = 4.69–7.63), frequently seeing drug using friends (OR = 3.72 for daily vs. never, 95% CI = 3.18–4.34) and having a difficult family relationship (OR = 2.03 for difficult vs. good, 95% CI = 1.63–2.52). Methadone dose was not associated with continued drug use while in treatment. The Chinese MMT programme appears to be having a positive influence on those clients who remain in treatment, but needs to explore strategies to increase accessibility.
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影响因子：
4.5
作者：
Liu H;Li J;Lu Z;Liu W;Zhang Z
通讯作者：
Zhang Z
影响因子：
5
作者：
BALL, JC;LANGE, WR;FRIEDMAN, SR
通讯作者：
FRIEDMAN, SR
影响因子：
4.2
作者：
Lin, Chunqing;Detels, Roger
通讯作者：
Detels, Roger
影响因子：
4.8
作者：
Royston, P
通讯作者：
Royston, P
影响因子：
4.4
作者：
Lin, Chunqing;Wu, Zunyou;Rou, Keming;Pang, Lin;Cao, Xiaobin;Shoptaw, Steven;Detels, Roger
通讯作者：
Detels, Roger