Associations among 25-year trends in diet, cholesterol and BMI from 140,000 observations in men and women in Northern Sweden.
Associations among 25-year trends in diet, cholesterol and BMI from 140,000 observations in men and women in Northern Sweden.
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DOI：
10.1186/1475-2891-11-40
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发表时间：
2012-06-11
影响因子：
5.4
通讯作者：
Winkvist A
中科院分区：
文献类型：
--
作者：
Johansson I;Nilsson LM;Stegmayr B;Boman K;Hallmans G;Winkvist A
在20世纪70年代，瑞典北方的男性是全世界心血管疾病（CVD）发病率最高的人群之一。1985年启动了一项结合面向人口和个人的活动的干预方案。同时，开始收集关于医疗风险因素、生活方式和人体测量的信息。今天，这些数据构成了世界上最大的基于人群样本的饮食摄入数据库之一，无论是在样本量还是随访期方面。该研究调查了1986年至2010年瑞典北方食物和营养素摄入、血清胆固醇和体重指数（BMI）的趋势。对超过140，000个观察结果进行了关于自我报告的食物和营养摄入量以及测量的体重、身高和血清胆固醇的横截面信息的汇编。在25年的时间里，对提供能量的营养素、有助于脂肪摄入的食物、血清胆固醇和BMI的趋势和趋势突破进行了评估。报告的脂肪摄入量在男女两性中都出现了两个显著的趋势突变：1986年至1992年期间有所下降，2002年（妇女）或2004年（男子）以来有所增加。碳水化合物的趋势相反，而蛋白质的摄入量在25年期间保持不变。食物摄入量对总脂肪摄入量的贡献出现了显著的趋势性变化。据报告，男女的葡萄酒摄入量都急剧增加（妇女的情况更是如此），男子的出口啤酒增加。1986 - 2004年期间，男女的BMI持续增加，而血清胆固醇水平下降，直到2007年保持不变，然后开始上升。血清胆固醇的增加与脂肪摄入量的增加相一致，特别是饱和脂肪和涂抹在面包和烹饪上的脂肪的摄入。瑞典北方的男性和女性在干预计划的前7年（1986-1992）中报告的脂肪摄入量减少。2004年后，男性和女性的脂肪摄入量都急剧增加，这与媒体对低碳水化合物高脂肪饮食的积极支持相吻合。胆固醇水平的降低和随后的增加与食物选择的时间趋势同时发生，而BMI的持续增加保持不变。这些危险因素的变化可能对心血管疾病（CVD）的一级和二级预防产生重要影响。
In the 1970s, men in northern Sweden had among the highest prevalences of cardiovascular diseases (CVD) worldwide. An intervention program combining population- and individual-oriented activities was initiated in 1985. Concurrently, collection of information on medical risk factors, lifestyle and anthropometry started. Today, these data make up one of the largest databases in the world on diet intake in a population-based sample, both in terms of sample size and follow-up period. The study examines trends in food and nutrient intake, serum cholesterol and body mass index (BMI) from 1986 to 2010 in northern Sweden. Cross-sectional information on self-reported food and nutrient intake and measured body weight, height, and serum cholesterol were compiled for over 140,000 observations. Trends and trend breaks over the 25-year period were evaluated for energy-providing nutrients, foods contributing to fat intake, serum cholesterol and BMI. Reported intake of fat exhibited two significant trend breaks in both sexes: a decrease between 1986 and 1992 and an increase from 2002 (women) or 2004 (men). A reverse trend was noted for carbohydrates, whereas protein intake remained unchanged during the 25-year period. Significant trend breaks in intake of foods contributing to total fat intake were seen. Reported intake of wine increased sharply for both sexes (more so for women) and export beer increased for men. BMI increased continuously for both sexes, whereas serum cholesterol levels decreased during 1986 - 2004, remained unchanged until 2007 and then began to rise. The increase in serum cholesterol coincided with the increase in fat intake, especially with intake of saturated fat and fats for spreading on bread and cooking. Men and women in northern Sweden decreased their reported fat intake in the first 7 years (1986–1992) of an intervention program. After 2004 fat intake increased sharply for both genders, which coincided with introduction of a positive media support for low carbohydrate-high-fat (LCHF) diet. The decrease and following increase in cholesterol levels occurred simultaneously with the time trends in food selection, whereas a constant increase in BMI remained unaltered. These changes in risk factors may have important effects on primary and secondary prevention of cardiovascular disease (CVD).
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影响因子：
16.2
作者：
Nettleton JA;McKeown NM;Kanoni S;Lemaitre RN;Hivert MF;Ngwa J;van Rooij FJ;Sonestedt E;Wojczynski MK;Ye Z;Tanaka T;Garcia M;Anderson JS;Follis JL;Djousse L;Mukamal K;Papoutsakis C;Mozaffarian D;Zillikens MC;Bandinelli S;Bennett AJ;Borecki IB;Feitosa MF;Ferrucci L;Forouhi NG;Groves CJ;Hallmans G;Harris T;Hofman A;Houston DK;Hu FB;Johansson I;Kritchevsky SB;Langenberg C;Launer L;Liu Y;Loos RJ;Nalls M;Orho-Melander M;Renstrom F;Rice K;Riserus U;Rolandsson O;Rotter JI;Saylor G;Sijbrands EJ;Sjogren P;Smith A;Steingrímsdóttir L;Uitterlinden AG;Wareham NJ;Prokopenko I;Pankow JS;van Duijn CM;Florez JC;Witteman JC;MAGIC Investigators;Dupuis J;Dedoussis GV;Ordovas JM;Ingelsson E;Cupples L;Siscovick DS;Franks PW;Meigs JB
通讯作者：
Meigs JB
影响因子：
39.3
作者：
Bjorck, Lena;Rosengren, Annika;Capewell, Simon
通讯作者：
Capewell, Simon
影响因子：
5
作者：
KEYS, A;MENOTTI, A;TOSHIMA, H
通讯作者：
TOSHIMA, H
影响因子：
11.1
作者：
Eriksson, M.;Holmgren, L.;Eliasson, M.
通讯作者：
Eliasson, M.
影响因子：
168.9
作者：
Kuulasmaa, K;Tunstall-Pedoe, H;Tuomilehto, J
通讯作者：
Tuomilehto, J