Resveratrol and Immune Cells: A Link to Improve Human Health.
Resveratrol and Immune Cells: A Link to Improve Human Health.
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DOI：
10.3390/molecules27020424
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发表时间：
2022-01-10
期刊：
影响因子：
--
通讯作者：
Cicero N
中科院分区：
文献类型：
--
作者：
Alesci A;Nicosia N;Fumia A;Giorgianni F;Santini A;Cicero N
近年来，由于多酚类物质可能具有抗氧化作用，人们研究了多酚类物质作为佐剂降低各种衰弱性疾病的风险因素。多酚代表了营养保健品和营养学中一个迷人且相对较新的研究课题，由于它们可以通过控制新陈代谢，体重，慢性疾病和细胞增殖来帮助保持健康，因此人们的兴趣迅速扩大。白藜芦醇是一种酚类化合物，主要存在于红葡萄的果肉、果皮、种子和茎中。它具有多种生物学作用，可用于预防各种疾病的开始或控制其症状。白藜芦醇可以影响多种炎症和非炎症反应，保护器官和组织，这要归功于它与免疫细胞的相互作用及其对SIRT1的活性。该化合物具有抗炎、抗氧化、抗凋亡、神经保护、心脏保护、抗癌和抗病毒特性，使其成为公共卫生中传统药物治疗的潜在辅助剂。本文旨在全面分析白藜芦醇在调节免疫细胞反应以促进人类身心健康方面的积极生物学效应和作用机制。
The use of polyphenols as adjuvants in lowering risk factors for various debilitating diseases has been investigated in recent years due to their possible antioxidant action. Polyphenols represent a fascinating and relatively new subject of research in nutraceuticals and nutrition, with interest rapidly expanding since they can help maintain health by controlling metabolism, weight, chronic diseases, and cell proliferation. Resveratrol is a phenolic compound found mostly in the pulp, peels, seeds, and stems of red grapes. It has a wide variety of biological actions that can be used to prevent the beginning of various diseases or manage their symptoms. Resveratrol can influence multiple inflammatory and non-inflammatory responses, protecting organs and tissues, thanks to its interaction with immune cells and its activity on SIRT1. This compound has anti-inflammatory, antioxidant, anti-apoptotic, neuroprotective, cardioprotective, anticancer, and antiviral properties, making it a potential adjunct to traditional pharmaceutical therapy in public health. This review aims to provide a comprehensive analysis of resveratrol in terms of active biological effects and mechanism of action in modifying the immune cellular response to promote human psychophysical health.
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影响因子：
2.2
作者：
Alesci, Alessio;Cicero, Nicola;Pergolizzi, Simona
通讯作者：
Pergolizzi, Simona
DOI：
10.1080/07315724.2021.1965503
发表时间：
2021-08-09
期刊：
JOURNAL OF THE AMERICAN NUTRITION ASSOCIATION
影响因子：
--
作者：
Alesci, Alessio;Fumia, Angelo;Cicero, Nicola
通讯作者：
Cicero, Nicola
影响因子：
5.1
作者：
Cho, N. H.;Shaw, J. E.;Malanda, B.
通讯作者：
Malanda, B.
影响因子：
5.6
作者：
Bigagli, Elisabetta;Cinci, Lorenzo;Luceri, Cristina
通讯作者：
Luceri, Cristina
DOI：
10.1097/mco.0000000000000444
发表时间：
2018-03
影响因子：
3.1
作者：
Beijers RJHCG;Gosker HR;Schols AMWJ
通讯作者：
Schols AMWJ