Mapping value based planning and extensively trained choice in the human brain.
Mapping value based planning and extensively trained choice in the human brain.
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DOI:
10.1038/nn.3068
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发表时间:
2012-03-11
影响因子:
25
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中科院分区:
文献类型:
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Investigations of the underlying mechanisms of choice in humans have focused on learning from prediction errors, and so the computational structure of value based planning is comparatively underexplored. Using behavioural and neuroimaging analyses of a minimax decision task, we show that the computational processes underlying forward planning are expressed in the anterior caudate nucleus as values of individual branching steps in a decision tree. In contrast, values represented in the putamen pertain solely to values learnt during extensive training. During actual choice, both striatal areas show a functional coupling to ventromedial prefrontal cortex, consistent with this region acting as a value comparator. Our findings point towards an architecture of choice in which segregated value systems operate in parallel in the striatum for planning and extensively trained choices, with medial prefrontal cortex integrating their outputs.
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