A new nematicidal compound produced by Streptomyces albogriseolus HA10002.
A new nematicidal compound produced by Streptomyces albogriseolus HA10002.
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一种由白链霉菌 HA10002 产生的新型杀线虫化合物
DOI：
10.1007/s10482-013-9890-8
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发表时间：
2013-05
影响因子：
2.6
通讯作者：
Bao, Shixiang
中科院分区：
文献类型：
--
作者：
Zeng, Qingfei;Huang, Huiqin;Zhu, Jun;Fang, Zhe;Sun, Qianguang;Bao, Shixiang
Strain HA10002 was isolated from mangrove sediment collected from Dongzhaigang Mangrove Reserve in Hainan, China. It was selected with potent nematicidal activity and was identified as Streptomyces albogriseolus. By bioassay-guided fractionation, a new active component A22-1(S1) against root-knot nematodes was separated from its fermentation broth. On the basis of spectroscopic analyses and comparison with the data from correlative literature, the structure of S1 was established to be 6'-methyl-fungichromin, named as fungichromin B in this paper. The LD50 values of fungichromin B to the 2-stage juveniles of Meloidogyne incognita and Meloidogyne javanica were 7.64 and 7.83 μg/ml, respectively. Further examination demonstrated fungichromin B still showed a wide antifungal spectrum, as with fungichromin.
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