Dielectric nanohole array metasurface for high-resolution near-field sensing and imaging.

Dielectric nanohole array metasurface for high-resolution near-field sensing and imaging.
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用于高分辨率近场感测和成像的介电纳米阵阵列递质。

DOI:
10.1038/s41467-021-23357-9
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发表时间:
2021-06-02
影响因子:
16.6
通讯作者:
Krauss TF
Krauss TF
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Conteduca D;Barth I;Pitruzzello G;Reardon CP;Martins ER;Krauss TF

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介电超表面支持共振,这种共振在远场波前整形以及近场传感和成像中得到了广泛的探索。他们的设计探索了局部共振和扩展共振之间的相互作用,并在 Q 因子和光局部化之间进行了典型的权衡;高品质因数对于折射率传感是理想的,而定位对于成像分辨率是理想的。在这里,我们表明,由非晶硅纳米孔阵列组成的介电超表面在这些要求之间提供了有利的权衡。我们设计并实现了超表面,以支持两种具有尖锐法诺共振的光学模式,表现出相对较高的 Q 因子和较强的空间限制,从而同时优化成像和生化传感的设备。对于传感应用,我们证明免疫球蛋白 G (IgG) 的检测限 (LOD) 低至 1 pg/ml;对于共振成像,我们展示了低于 1μm 的空间分辨率,并且可以清晰地分辨单个大肠杆菌。低 LOD 和高空间分辨率的结合为将细胞研究扩展到微生物学领域提供了新的机会,例如微生物学领域。用于研究抗菌药物敏感性。介电超表面对于传感和成像具有不同的品质因数和光定位要求。在这里,作者提出了一种介电超表面,支持两种具有尖锐 Fano 共振的光学模式,可实现高 Q 因子和强空间限制,从而实现传感和成像。
Dielectric metasurfaces support resonances that are widely explored both for far-field wavefront shaping and for near-field sensing and imaging. Their design explores the interplay between localised and extended resonances, with a typical trade-off between Q-factor and light localisation; high Q-factors are desirable for refractive index sensing while localisation is desirable for imaging resolution. Here, we show that a dielectric metasurface consisting of a nanohole array in amorphous silicon provides a favourable trade-off between these requirements. We have designed and realised the metasurface to support two optical modes both with sharp Fano resonances that exhibit relatively high Q-factors and strong spatial confinement, thereby concurrently optimizing the device for both imaging and biochemical sensing. For the sensing application, we demonstrate a limit of detection (LOD) as low as 1 pg/ml for Immunoglobulin G (IgG); for resonant imaging, we demonstrate a spatial resolution below 1 µm and clearly resolve individual E. coli bacteria. The combined low LOD and high spatial resolution opens new opportunities for extending cellular studies into the realm of microbiology, e.g. for studying antimicrobial susceptibility. Dielectric metasurfaces have different Q-factor and light localisation requirements for sensing and imaging. Here, the authors present a dielectric metasurface, supporting two optical modes with sharp Fano resonances for high Q-factors and strong spatial confinement, allowing both sensing and imaging.
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