Colour Me Blue: The History and the Biotechnological Potential of Pyocyanin.

Colour Me Blue: The History and the Biotechnological Potential of Pyocyanin.
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DOI:
10.3390/molecules26040927
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发表时间:
2021-02-10
期刊:
Molecules (Basel, Switzerland)
影响因子:
--
通讯作者:
Vasconcelos U
Vasconcelos U
中科院分区:
其他
文献类型:
--
作者:
Gonçalves T;Vasconcelos U

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Pyocyanin是第一个被描述的天然非那嗪。该分子由大约95%的铜绿假单胞菌菌株合成。从发现到现在,花青素的特点是非常丰富和前卫的历史,其中包括它在抗菌治疗中的应用,甚至在青霉素的发现开启了抗生素治疗的时代之前,以及它在电流产生中的应用。这种颜料呈现出浓郁的蓝色,易于获得,是本综述的主题,旨在叙述其历史,揭示其机制,并提出在工程,生物学和生物技术不同领域应用的新视野。
Pyocyanin was the first natural phenazine described. The molecule is synthesized by about 95% of the strains of Pseudomonas aeruginosa. From discovery up to now, pyocyanin has been characterised by a very rich and avant-garde history, which includes its use in antimicrobial therapy, even before the discovery of penicillin opened the era of antibiotic therapy, as well as its use in electric current generation. Exhibiting an exuberant blue colour and being easy to obtain, this pigment is the subject of the present review, aiming to narrate its history as well as to unveil its mechanisms and suggest new horizons for applications in different areas of engineering, biology and biotechnology.
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