The use of cell phone support for non-adherent HIV-infected youth and young adults: an initial randomized and controlled intervention trial.

The use of cell phone support for non-adherent HIV-infected youth and young adults: an initial randomized and controlled intervention trial.
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DOI:
10.1007/s10461-013-0661-3
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发表时间:
2014-04
期刊:
影响因子:
4.4
通讯作者:
Clark, Leslie F.
Clark, Leslie F.
中科院分区:
医学2区
文献类型:
--
作者:
Belzer, Marvin E.;Naar-King, Sylvie;Olson, Johanna;Sarr, Moussa;Thornton, Sarah;Kahana, Shoshana Y.;Gaur, Aditya H.;Clark, Leslie F.

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这项随机行为试验研究了艾滋病毒感染者(YLH)是否接受研究资助的电话计划的手机支持,与对照组相比,在24周的干预期间和干预后24周内表现出更好的依从性和病毒控制。周一至周五的电话确认服用药物,提供解决问题的支持,并介绍服务,以解决依从性障碍。在37名参与者(年龄15-24岁)中,62%为男性,70%为非洲裔美国人。在过去的一个月里,干预组在24周和48周时的自我报告依从性显著高于对照组(P = 0.007),log 10 HIV VL在24周(2.82 vs 4.52 P = 0.002)和48周(3.23 vs 4.23 P = 0.043)时显著降低。在为期48周的研究中,依从性和病毒载量显示出中等至大的效应量。这是第一项证明使用青少年友好技术可持续临床显著降低HIV VL的研究。
This randomized behavioral trial examined whether youth living with HIV (YLH) receiving cell-phone support with study funded phone plans, demonstrated improved adherence and viral control during the 24 week intervention and 24 weeks post-intervention compared to controls. Monday through Friday phone calls confirmed medications were taken, provided problem-solving support, and referred to services to address adherence barriers. Of 37 participants (ages 15–24), 62 % were male and 70 % were African American. Self-reported adherence was significantly higher in the intervention group compared to the control at 24 and 48 weeks for the past month (P = 0.007) and log 10 HIV VL was significantly lower at both 24 weeks (2.82 versus 4.52 P = 0.002) and 48 weeks (3.23 versus 4.23 P = 0.043). Adherence and viral load showed medium to large effect sizes across the 48 week study. This is the first study to demonstrate sustained clinically significant reductions in HIV VL using youth friendly technology.
改善感染人类免疫缺陷病毒的青少年的健康结果:针对多种危险行为的动机干预的多中心随机试验。
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