Improving health outcomes for youth living with the human immunodeficiency virus: a multisite randomized trial of a motivational intervention targeting multiple risk behaviors.
Improving health outcomes for youth living with the human immunodeficiency virus: a multisite randomized trial of a motivational intervention targeting multiple risk behaviors.
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改善感染人类免疫缺陷病毒的青少年的健康结果：针对多种危险行为的动机干预的多中心随机试验。
DOI：
10.1001/archpediatrics.2009.212
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发表时间：
2009-12
影响因子：
--
通讯作者：
Belzer, Marvin E.
中科院分区：
文献类型：
--
作者：
Naar-King, Sylvie;Parsons, Jeffrey T.;Murphy, Debra A.;Chen, Xinguang;Harris, D. Robert;Belzer, Marvin E.
旨在确定“健康选择”（一种针对多种风险行为的动机性访谈干预措施）是否可以改善人类免疫缺陷病毒 (HIV) 病毒载量。随机、两组重复测量设计，分析 2005 年至 2007 年收集的基线数据以及 6 个月和 9 个月的随访数据。美国五家青少年医学 HIV 诊所。纳入了至少具有 3 种危险行为（不遵守 HIV 药物治疗、药物滥用和无保护性行为）中的 1 种的方便样本。样本年龄在 16 至 24 岁之间，主要是非裔美国人。在 205 名受试者中，有 19 名未完成基线数据收集，最终样本量为 186 名。感染艾滋病毒的年轻人被随机分配接受干预加专业护理 (n = 94) 或单独接受专业护理 (n = 92)。干预组的 3 个月和 6 个月随访率分别为 86% 和 82%，对照组为 81% 和 73%。健康选择是一项为期 10 周、为期 4 期的基于个人诊所的动机访谈干预措施。动机访谈是一种旨在引发和强化变革的内在动机的沟通方法。血浆病毒载量。与对照条件下的青少年相比，随机分配到“健康选择”的青少年在干预后 6 个月时病毒载量显着下降（β = -0.36，t = -2.15，P = .03），而那些开具抗逆转录病毒药物的患者显示出最低的病毒载量。 9 个月时差异不再显着。针对多种危险行为的动机性访谈干预措施使感染艾滋病毒的青少年的病毒载量得到了短期改善。
To determine if Healthy Choices, a motivational interviewing intervention targeting multiple risk behaviors, improved human immunodeficiency virus (HIV) viral load. A randomized, 2-group repeated measures design with analysis of data from baseline and 6- and 9-month follow-up collected from 2005 to 2007. Five US adolescent medicine HIV clinics. A convenience sample with at least 1 of 3 risk behaviors (nonadherence to HIV medications, substance abuse, and unprotected sex) was enrolled. The sample was aged 16 to 24 years and primarily African American. Of the 205 enrolled, 19 did not complete baseline data collections, for a final sample size of 186. Young people living with HIV were randomized to the intervention plus specialty care (n = 94) or specialty care alone (n = 92). The 3- and 6-month follow-up rates, respectively, were 86% and 82% for the intervention group and 81% and 73% for controls. Healthy Choices was a 4-session individual clinic-based motivational interviewing intervention delivered during a 10-week period. Motivational interviewing is a method of communication designed to elicit and reinforce intrinsic motivation for change. Plasma viral load. Youth randomized to Healthy Choices showed a significant decline in viral load at 6 months postintervention compared with youth in the control condition (β = −0.36, t = −2.15, P = .03), with those prescribed antiretroviral medications showing the lowest viral loads. Differences were no longer significant at 9 months. A motivational interviewing intervention targeting multiple risk behaviors resulted in short-term improvements in viral load for youth living with HIV.
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DOI：
10.2471/blt.07.050120
发表时间：
2008-12-01
期刊：
Bulletin of the World Health Organization: International Journal of Public Health
影响因子：
--
作者：
Charles, Macarthur;Noel, Francine;Fitzgerald, Daniel W
通讯作者：
Fitzgerald, Daniel W
影响因子：
4.9
作者：
Ellis, DA;Naar-King, S;Secord, E
通讯作者：
Secord, E
影响因子：
5.9
作者：
Morgenstern, Jon;Irwin, Thomas W.;Schulz-Heik, Jay
通讯作者：
Schulz-Heik, Jay
DOI：
10.1080/09540120020018161
发表时间：
2001-02-01
影响因子：
1.7
作者：
Murphy, DA;Wilson, CM;Belzer, M
通讯作者：
Belzer, M
DOI：
10.1080/09540120701593489
发表时间：
2008-01-01
影响因子：
1.7
作者：
DiIorio, C.;Mccarty, F.;Lundberg, B.
通讯作者：
Lundberg, B.