Laser-direct-writing to enable filtration in paper-based devices
Laser-direct-writing to enable filtration in paper-based devices
复制标题
激光直写可在纸质设备中实现过滤
DOI：
10.1117/12.2508753
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发表时间：
2019
期刊：
影响因子：
--
通讯作者：
Galanis P
中科院分区：
文献类型：
--
作者：
Galanis P
我们报告了基于激光的直接写入（LDW）技术的使用，该技术允许制造多孔屏障，从而实现纸质微流体装置内的在线过滤。在多孔基材，即硝化纤维素膜，通过局部沉积的光聚合物，随后通过从激光源曝光聚合的障碍。光聚合物沉积参数的调整决定了屏障的孔隙率，当仔细设计并集成在流体通道内时，屏障可以充当过滤器，其能够完全阻挡、选择性流动或控制分离行进通过通道的流体内的不同尺寸的颗粒。我们已经成功地确定了用于创建屏障的制造参数，该屏障允许过滤两种不同类型的颗粒，即分散在水溶液中的尺寸为40、100和200 nm的Au纳米颗粒和尺寸为200 nm和1 μm的乳胶微珠。我们还报告了使用可变孔隙率屏障选择性分离乳胶微珠和Aunanoparticles，从而显示了这种技术在这种纸基微流体装置中实现在线过滤的有用性。
We report the use of a laser-based direct-write (LDW) technique that allows the fabrication of porous barriers, which enable in-line filtration within a paper-based microfluidic device. The barriers were produced within porous substrates, namely nitrocellulose membranes, via local deposition of a photo-polymer that was subsequently polymerised by exposure from a laser source. Adjustment of the photo-polymer deposition parameters determines the porosity of the barriers, which, when carefully designed and integrated within a fluidic channel, can act as filters that enable either complete blocking, selective flow or controlled separation of particles of different sizes within a fluid travelling through the channel. We have successfully identified the fabrication parameters for the creation of barriers that allow the filtration of two different types of particles, Au-nanoparticles with sizes of 40, 100 and 200 nm and latex microbeads with sizes of 200 nm and 1 μm, dispersed within an aqueous solution. We also report the use of a variable-porosity barrier for selective separation of latex microbeads from Aunanoparticles, thereby showing the usefulness of this technique for enabling in-line filtration in such paper-based microfluidic devices.
影响因子：
8.4
作者：
Andersson, H;van der Wijngaart, W;Stemme, G
通讯作者：
Stemme, G
DOI：
10.1111/j.1751-2824.2008.00195.x
发表时间：
2008-01-01
期刊：
ISBT SCIENCE SERIES, VOL 3, NO 2: INTRODUCTION TO BLOOD TRANSFUSION TECHNOLOGY
影响因子：
--
作者：
Hardwick, J.
通讯作者：
Hardwick, J.
影响因子：
3.2
作者：
He, Peijun J. W.;Katis, Ioannis N.;Sones, Collin L.
通讯作者：
Sones, Collin L.