Diagnosis and challenges of polycystic ovary syndrome in adolescence.
Diagnosis and challenges of polycystic ovary syndrome in adolescence.
复制标题
多囊卵巢综合征在青春期的诊断和挑战。
DOI：
10.1055/s-0034-1371091
复制
发表时间：
2014-05
影响因子：
2.7
通讯作者：
Oberfield SE
中科院分区：
文献类型：
--
作者：
Agapova SE;Cameo T;Sopher AB;Oberfield SE
尽管多囊卵巢综合征(PCOS)的诊断标准多年来已变得不那么严格，但确定青少年的最低诊断特征仍然是一个有争议的领域。特别值得关注的是，许多被认为是多囊卵巢综合征的诊断特征可能会随着时间的推移而演变，并在月经初潮后的头几年发生变化。然而，由于肥胖、胰岛素抵抗和血脂异常等相关发病率可能从早期干预中受益，因此尝试定义可能有发展为多囊卵巢综合征的风险的年轻女性是有意义的。诊断工具的相对效用，如持续无排卵周期、高雄激素血症、高雄激素血症(多毛症、痤疮或脱发)或卵巢超声检查结果，在青少年中尚未确定。一些人建议，即使使用最严格的标准，多囊卵巢综合征的诊断可能也不适用于18岁以下的青少年。此外，证据并不一定支持青少年缺乏治疗多囊卵巢综合征会导致不良后果，因为符合多囊卵巢综合征的特征通常会随着时间的推移而消失。目前的数据将有助于确定是否有可能建立可靠的标准来诊断青少年的多囊卵巢综合征。
Although the diagnostic criteria for polycystic ovary syndrome (PCOS) have become less stringent over the years, determination of the minimum diagnostic features in adolescents is still an area of controversy. Of particular concern is that many of the features considered to be diagnostic for PCOS may evolve over time and change during the first few years after menarche. Nonetheless, attempts to define young women who may be at risk for development of PCOS is pertinent since associated morbidity such as obesity, insulin resistance, and dyslipidemia may benefit from early intervention. The relative utility of diagnostic tools such as persistence of anovulatory cycles, hyperandrogenemia, hyperandrogenism (hirsutism, acne, or alopecia), or ovarian findings on ultrasound is not established in adolescents. Some suggest that even using the strictest criteria, the diagnosis of PCOS may not valid in adolescents younger than 18 years. In addition, evidence does not necessarily support that lack of treatment of PCOS in younger adolescents will result in untoward outcomes since features consistent with PCOS often resolve with time. The presented data will help determine if it is possible to establish firm criteria which may be used to reliably diagnose PCOS in adolescents.
登录
查看更多内容
影响因子：
4.4
作者：
Brown, Michele;Park, Alice S.;Shayya, Rana F.;Wolfson, Tanya;Su, H. Irene;Chang, R. Jeffrey
通讯作者：
Chang, R. Jeffrey
影响因子：
6.7
作者：
Codner, Ethel;Villarroel, Claudio;Cassorla, Fernando
通讯作者：
Cassorla, Fernando
影响因子：
1.8
作者：
Bronstein, Jason;Tawdekar, Sonali;Shah, Bina
通讯作者：
Shah, Bina
影响因子：
6.1
作者：
De Leo, Vincenzo;Musacchio, M. C.;Petraglia, F.
通讯作者：
Petraglia, F.
影响因子：
6.1
作者：
Eilertsen, Tina B.;Vanky, Eszter;Carlsen, Sven M.
通讯作者：
Carlsen, Sven M.