Ovarian imaging by magnetic resonance in adolescent girls with polycystic ovary syndrome and age-matched controls.
Ovarian imaging by magnetic resonance in adolescent girls with polycystic ovary syndrome and age-matched controls.
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DOI：
10.1002/jmri.23992
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发表时间：
2013-09
影响因子：
4.4
通讯作者：
Chang, R. Jeffrey
中科院分区：
文献类型：
--
作者：
Brown, Michele;Park, Alice S.;Shayya, Rana F.;Wolfson, Tanya;Su, H. Irene;Chang, R. Jeffrey
利用磁共振（MR）成像比较多囊卵巢综合征（PCOS）和非PCOS青春期女孩的卵巢形态。在21例青春期女孩（12-18岁）和19例青春期PCOS（诊断基于毛发过度生长和不规则月经周期）的卵巢体积，每个卵巢的窦卵泡计数（AFC）和卵泡大小进行了评估。在1.5 T或3 T下进行MR成像，并采集6 mm层厚的轴向或成角轴向单次激发回波序列自旋回波图像。在一个受试者子集中，还获得了2 mm图像。PCOS和非PCOS组采用混合影响回归进行比较。与非PCOS受试者相比，PCOS受试者每个卵巢的平均AFC和卵巢体积显著更大。两组间的平均卵泡大小相似。在2/19例PCOS受试者和9/21例非PCOS受试者中观察到卵泡超过10 mm。与6 mm切片厚度相比，在2 mm切片厚度下获得的图像中检测到一致的较高卵泡计数。在青春期，卵巢的MR成像显示了PCOS女孩与非PCOS女孩之间的明显差异。磁共振成像可能有助于评估经阴道超声禁忌的年轻患者。
To compare ovarian morphology in adolescent girls with and without polycystic ovary syndrome (PCOS) using magnetic resonance (MR) imaging. In 21 adolescent girls (12–18 years) without and 19 adolescents with PCOS (diagnosis based on excessive hair growth and irregular menstrual cycles) ovarian volume, antral follicle count (AFC) per ovary, and follicle size were evaluated. MR imaging was performed at 1.5 T or 3 T and axial or angled-axial single-shot echo-train spin echo images of 6 mm slice thickness were acquired. In a subset of subjects, 2 mm images were also obtained. PCOS and non-PCOS groups were compared using mixed affects regression. Mean AFC per ovary and ovarian volume were substantially greater in PCOS subjects compared to non-PCOS subjects. Mean follicle size was similar between groups. Follicles exceeding 10 mm were seen in 2/19 PCOS subjects versus 9/21 non-PCOS subjects. Consistently higher follicle counts were detected in images obtained at 2 mm compared to 6 mm slice thickness. In adolescence MR imaging of the ovary reveals distinct differences between girls with and without PCOS. MR imaging may help evaluate young patients in whom transvaginal ultrasound is contraindicated.
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