Helminth-Tuberculosis Co-infection: An Immunologic Perspective.
Helminth-Tuberculosis Co-infection: An Immunologic Perspective.
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DOI:
10.1016/j.it.2016.07.005
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发表时间:
2016-09
影响因子:
16.8
通讯作者:
Nutman TB
中科院分区:
文献类型:
--
作者:
Babu S;Nutman TB
Over 2 billion people worldwide are infected with helminths (worms). Similarly, infection with Mycobacterium tuberculosis (Mtb) occurs in over a third of the world's population, often with a great degree of geographical overlap with helminth infection. Interestingly, the responses induced by the extracellular helminths and those induced by the intracellular Mtb are often mutually antagonistic and, as a consequence, can result in impaired (or cross-regulated) host responses to either of the infecting pathogens. In this review, we outline the nature of the immune responses induced by infections with helminths and tuberculosis (TB) and then provide data from both experimental models and human studies that illustrate how the immune response engendered by helminth parasites modulates Mtb-specific responses in helminth-TB co-infection.
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影响因子:
2.2
作者:
Babu S;Nutman TB
通讯作者:
Nutman TB
影响因子:
5.5
作者:
Elias, Daniel;Britton, Sven;Akuffo, Hannah
通讯作者:
Akuffo, Hannah
影响因子:
3.8
作者:
Frantz, Fabiani G.;Rosada, Rogerio S.;Faccioli, Lucia H.
通讯作者:
Faccioli, Lucia H.
影响因子:
3.8
作者:
Abate E;Belayneh M;Idh J;Diro E;Elias D;Britton S;Aseffa A;Stendahl O;Schön T
通讯作者:
Schön T
DOI:
10.1097/aci.0b013e32831f44a6
发表时间:
2009-02
影响因子:
2.8
作者:
Cooper PJ
通讯作者:
Cooper PJ