Risk and protective factors for health-related quality of life among persons aging with HIV.

Risk and protective factors for health-related quality of life among persons aging with HIV.
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DOI:
10.1080/09540121.2017.1381333
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发表时间:
2018-04
期刊:
影响因子:
1.7
通讯作者:
Rhodes SD
Rhodes SD
中科院分区:
医学4区
文献类型:
--
作者:
Nguyen AL;McNeil CJ;Han SD;Rhodes SD

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对于艾滋病毒感染者,与健康有关的生活质量(HRQOL)可能受到身体和精神状况的威胁,但可能受到积极的心理特征的保护。我们对老年艾滋病毒感染者HRQOL的风险和保护因素进行了探索性研究。对来自拉什艾滋病毒和老龄化差异卓越中心(CEDHA)的基线数据进行了横断面分析,CEDHA是一个基于社区的队列,年龄≥50岁的艾滋病毒感染者(n = 176)。分析检查了风险/保护因素与两种结果之间的关系(即,自我报告的健康状况[SRHS]和健康日指数[HDI])。在双变量分析中,健康状况良好/极佳与不吸烟(p = 0.002)、生活目标更高(p = 0.006)、受教育程度更高(p = 0.007)、抑郁症状更少(p = 0.004)、残疾更少(p = 0.000)和孤独感更少(p = 0.002)相关。男性(p = 0.03)和非裔美国人/黑人(p = 0.03)报告的人类发展指数较高。在双变量分析中,抑郁症状(p = 0.000)、残疾(p = 0.002)、不良生活事件(p = 0.0103)和孤独(p = 0.000)较少与HDI较高相关。在逻辑回归模型中,调整协变量后,生活目标更大,残疾更少,不吸烟与SRHS更好相关。对于非裔美国人/黑人,在调整协变量后,抑郁症状和残疾较少与较高的HDI相关。残疾、抑郁、吸烟状况、种族/民族和生活目的与HRQOL显著相关。研究结果支持需要研究,以检查文化解释的生活质量的影响,并侧重于促进身体功能,戒烟和心理健康的人与艾滋病毒的老年人。
For persons living with HIV, health-related quality of life (HRQOL) may be threatened by physical and mental conditions but may be protected by positive psychological traits. We performed an exploratory look at the risk and protective factors for HRQOL in older adults living with HIV. Cross-sectional analyses of baseline data from the Rush Center of Excellence on Disparities in HIV and Aging (CEDHA), a community-based cohort of persons ages ≥50 living with HIV (n = 176) were performed. Analyses examined the relationship between risk/protective factors and two outcomes (i.e., self-reported health status [SRHS] and the healthy days index [HDI]). Having good/excellent health was associated with being a non-smoker (p = 0.002), greater purpose in life (p = 0.006), higher education (p = 0.007), fewer depressive symptoms (p = 0.004), fewer disabilities (p = 0.000), and less loneliness (p = 0.002) in bivariate analyses. Males (p = 0.03) and African Americans/Blacks (p = 0.03) reported higher HDI. Fewer depressive symptoms (p = 0.000), disabilities (p = 0.002), adverse life events (p = 0.0103), and loneliness (p = 0.000) were associated with higher HDI in bivariate analyses. In a logistic regression model, greater purpose in life, fewer disabilities, and being a non-smoker were associated with better SRHS after adjusting for covariates. For African Americans/Blacks, having fewer depressive symptoms and disabilities were associated with higher HDI after adjusting for covariates. Disabilities, depression, smoking status, race/ethnicity, and purpose in life were significantly associated with HRQOL. Findings support the need for research to examine the influence of cultural interpretations of life quality and focus on promoting physical function, smoking cessation, and psychological wellness in persons aging with HIV.
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