The Wide Range Achievement Test-4 Reading subtest "holds" in HIV-infected individuals.
The Wide Range Achievement Test-4 Reading subtest "holds" in HIV-infected individuals.
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DOI：
10.1080/13803395.2014.960370
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发表时间：
2014
影响因子：
2.2
通讯作者：
HNRP Group
中科院分区：
文献类型：
--
作者：
Casaletto KB;Cattie J;Franklin DR;Moore DJ;Woods SP;Grant I;Heaton RK;HNRP Group
为了检测与艾滋病毒相关的神经认知能力下降，准确估计个体病前的认知功能水平非常重要。虽然以前的研究假设文字阅读测试是有效的和稳定的指标，在艾滋病毒感染的发病前的能力，其他人群的研究发现，情况并非总是如此。因此，重要的是要实证检验的有效性字阅读测试的发病前功能，特别是在艾滋病毒人群的估计。广泛成就测验-4项阅读分测验对150名HIV血清阳性（HIV+）和76名HIV血清阴性（HIV-）年龄、教育和性别匹配的基线参与者进行了沿着全面的神经认知评估（WRAT-4阅读）; 48名HIV+个体的亚组完成了第二次研究访问（M=14.4个月），其中施用了WRAT-4的替代版本。尽管HIV阳性个体的当前神经认知功能比HIV阴性个体差，但两组的WRAT-4阅读表现相当。纵向上，HIV+参与者证明疾病和神经心理功能得到改善，但WRAT-4阅读表现出较强的重测信度，没有实践效果，并且在初始和随访评估之间没有差异。在阅读能力上的重测差异很小，并且与神经认知能力的变化或HIV疾病的变化无关。我们没有发现HIV感染者WRAT-4阅读能力下降的证据，尽管HIV+/HIV-组在神经认知功能方面存在差异。此外，HIV阳性个体的阅读表现在研究访视中表现一致。这些结果开始支持WRAT-4阅读子测试作为HIV+个体病前认知功能指标的有效性。
In order to detect HIV-associated neurocognitive decline, it is important to accurately estimate individuals’ premorbid levels of cognitive functioning. Although previous studies have operated under the assumption that word reading tests are valid and stable indicators of premorbid abilities in HIV infection, studies of other populations have found this is not always the case. Therefore, it is important to empirically examine the validity of word reading tests as estimates of premorbid functioning specifically within the HIV population. The Wide Range Achievement Test-4 Reading subtest (WRAT-4 Reading) was administered along with comprehensive neurocognitive assessments to 150 HIV seropositive (HIV+) and 76 HIV seronegative (HIV-) age-, education-, and sex-matched participants at baseline; a subset of 48 HIV+ individuals completed a second study visit (M=14.4 months), in which the alternate version of the WRAT-4 was administered. Although HIV+ individuals evidenced worse current neurocognitive functioning than HIV- participants, WRAT-4 Reading performance was comparable between groups. Longitudinally, HIV+ participants evidenced improved disease and neuropsychological functioning, yet WRAT-4 Reading demonstrated strong test-retest reliability, no practice effect, and did not differ between the initial and follow-up assessments. Test-retest differences in reading performance were minor and not associated with changes in neurocognitive performance or changes in HIV disease. We found no evidence of WRAT-4 Reading performance decline in HIV infection, despite HIV+/HIV- group differences in neurocognitive functioning. Additionally, reading performances among HIV+ individuals demonstrated consistency across study visits. These results begin to support the validity of the WRAT-4 Reading subtest as an indicator of premorbid cognitive functioning in HIV+ individuals.
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DOI：
10.1080/13803390802375557
发表时间：
2009-07-01
影响因子：
2.2
作者：
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通讯作者：
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DOI：
10.1080/13803395.2010.535504
发表时间：
2011-06
影响因子：
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10.1017/s1355617702860131
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影响因子：
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