Giardiasis as a neglected disease in Brazil: Systematic review of 20 years of publications.
Giardiasis as a neglected disease in Brazil: Systematic review of 20 years of publications.
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DOI：
10.1371/journal.pntd.0006005
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发表时间：
2017-10
影响因子：
3.8
通讯作者：
Singer SM
中科院分区：
文献类型：
--
作者：
Coelho CH;Durigan M;Leal DAG;Schneider AB;Franco RMB;Singer SM
贾第鞭毛虫病是一种肠道感染，每年影响全球2亿多人；它是由鞭毛原生动物十二指肠贾第鞭毛虫引起的。在热带国家和低收入或中等收入地区，如巴西，它的流行率可能很高。目前还没有关于巴西患者、动物或水源中十二指肠球虫存在的系统评价。这项系统审查是根据系统审查和荟萃分析首选报告项目(PRISMA)提出的建议进行的。作为我们搜索的数据库，我们使用了PubMed、Embase、Scope us和巴西数据库SciELO，并使用了关键词Giardia*和巴西。这项系统回顾确定了与水中十二指肠寄生虫、动物贾第鞭毛虫病、巴西各地区贾第鞭毛虫病流行率、人类分离菌株的基因分型以及土著人口贾第鞭毛虫病相关的研究。我们还提出了一个基于基因分析的巴西十二指肠吸虫传播网络。这是近20年来首次发表关于巴西十二指肠寄生虫发生情况的综述，涉及流行率、分子流行病学和寄生虫检测的分析方法等相关问题。贾第鞭毛虫病是一种肠道疾病，影响着全球数百万人，包括儿童。它的主要传播途径是通过摄入被原生动物十二指肠原虫污染的食物或水。传播不需要动物宿主，尽管从动物到人类的传播(人畜传播)已被确认为人类贾第鞭毛虫病的重要媒介。这项研究基于过去20年在巴西发表的研究，全面描述了贾第鞭毛虫病在巴西的影响。我们描述了贾第虫在人类(包括土著人口)、动物和供水中的流行情况。此外，我们根据先前在动物和人类宿主以及环境样本中识别的基因数据，创建了疾病的传播网络模型。这里汇编的数据将有助于设计预防贾第鞭毛虫病在巴西传播的政策。
Giardiasis is an intestinal infection that affects more than two hundred million people annually worldwide; it is caused by the flagellated protozoan Giardia duodenalis. In tropical countries and in low or middle-income settings, like Brazil, its prevalence can be high. There is currently no systematic review on the presence of G. duodenalis in patients, animals or water sources in Brazil. This systematic review was performed according to recommendations established by Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). As databases for our searches, we have used PubMed, Embase, Scopus and the Brazilian database SciELO using the keywords Giardia* and Brazil. This systematic review identified research studies related to G. duodenalis in water, giardiasis in animals, prevalence of giardiasis across Brazilian regions, genotyping of strains isolated in humans, and giardiasis in indigenous populations. We also propose a network of G. duodenalis transmission in Brazil based on genotypes analyses. This is the first time within the last twenty years that a review is being published on the occurrence of G. duodenalis in Brazil, addressing relevant issues such as prevalence, molecular epidemiology and analytical methods for parasite detection. Giardiasis is an intestinal disease that affect millions of people worldwide, including children. Its main route of transmission is by ingestion of food or water contaminated with the protozoan G. duodenalis. Transmission does not require an animal host, although transmission from animals to human (zoonotic transmission) has been confirmed as an important vector of human giardiasis. This study is a comprehensive description of the impact of giardiasis in Brazil based on studies published in the country from the past 20 years. We describe Giardia prevalence in humans (including indigenous populations), animals and water supplies. In addition, we create a transmission network model for the disease, based on genotype data previously identified in animal and human hosts as well as in environmental samples. The data compiled here will be useful for design of policies to prevent giardiasis transmission in Brazil.
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影响因子：
3.2
作者：
David ÉB;Guimarães S;de Oliveira AP;Goulart de Oliveira-Sequeira TC;Nogueira Bittencourt G;Moraes Nardi AR;Martins Ribolla PE;Bueno Franco RM;Branco N;Tosini F;Bella A;Pozio E;Cacciò SM
通讯作者：
Cacciò SM
影响因子：
11.8
作者：
Acosta, Angel Mendez;Chavez, Cesar Banda;Shrestha, Sanjaya Kumar
通讯作者：
Shrestha, Sanjaya Kumar
DOI：
10.1590/s1984-29612015051
发表时间：
2015-09-01
期刊：
Revista Brasileira de Parasitologia Veterinária
影响因子：
--
作者：
Almeida, Jonatas Campos;Martins, Felippe Danyel Cardoso;Freire, Roberta Lemos
通讯作者：
Freire, Roberta Lemos
影响因子：
4.5
作者：
Coimbra, Carlos E. A., Jr.;Santos, Ricardo Ventura;Horta, Bernardo L.
通讯作者：
Horta, Bernardo L.
影响因子：
0.7
作者：
Barbosa, Alynne da Silva;Pissinatti, Alcides;Reis Amendoeira, Maria Regina
通讯作者：
Reis Amendoeira, Maria Regina