Primary amenorrhea in anorexia nervosa: impact on characteristic masculine and feminine traits.
Primary amenorrhea in anorexia nervosa: impact on characteristic masculine and feminine traits.
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DOI：
10.1002/erv.2263
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发表时间：
2014-01
影响因子：
5.3
通讯作者：
Klump, Kelly L.
中科院分区：
文献类型：
--
作者：
Baker, Jessica H.;Sisk, Cheryl L.;Thornton, Laura M.;Brandt, Harry;Crawford, Steven;Fichter, Manfred M.;Halmi, Katherine A.;Johnson, Craig;Jones, Ian;Kaplan, Allan S.;Mitchell, James E.;Strober, Michael;Treasure, Janet;Woodside, D. Blake;Berrettini, Wade H.;Kaye, Walter H.;Bulik, Cynthia M.;Klump, Kelly L.
动物研究表明，青春期的性腺激素对男性和女性特征的发展有影响。然而，目前还不清楚类似的过程是否发生在人类身上。我们研究了经常经历原发闭经的神经性厌食症(AN)女性在成年后是否由于青春期性腺激素的减少/缺乏而在心理特征上表现出减弱的女性化。使用基于有无原发闭经的一般线性模型，对患有AN的妇女的许多心理特征进行了比较。虽然有原发闭经的妇女表现出比没有原发闭经的妇女更低的焦虑评分，但总的来说，结果并没有提供有原发闭经的妇女减弱女性化的证据。未来的研究应该利用新的技术和直接的激素测量来探索青春期性腺激素对男性和女性特征的影响。
Animal studies indicate gonadal hormones at puberty have an effect on the development of masculine and feminine traits. However, it is unknown whether similar processes occur in humans. We examined whether women with anorexia nervosa (AN), who often experience primary amenorrhea, exhibit attenuated feminization in their psychological characteristics in adulthood due to the decrease/absence of gonadal hormones at puberty. Women with AN were compared on a number of psychological characteristics using General Linear Models based on the presence/absence of primary amenorrhea. Although women with primary amenorrhea exhibited lower anxiety scores than those without primary amenorrhea, in general, results did not provide evidence of attenuated feminization in women with AN with primary amenorrhea. Future research should utilize novel techniques and direct hormone measurement to explore the effects of pubertal gonadal hormones on masculine and feminine traits.
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影响因子：
3.7
作者：
Neufang, Susanne;Specht, Karsten;Konrad, Kerstin
通讯作者：
Konrad, Kerstin
影响因子：
5.1
作者：
Katzman, DK;Lambe, EK;Zipursky, RB
通讯作者：
Zipursky, RB
影响因子：
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作者：
Kaye, Walter H.;Bulik, Cynthia M.;Jones, Ian
通讯作者：
Jones, Ian
影响因子：
10.6
作者：
Kaye, WH;Lilenfeld, LR;McConaha, CW
通讯作者：
McConaha, CW
影响因子：
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作者：
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通讯作者：
TANNER, JM