The evolution of plasticity of dauer larva developmental arrest in the nematode Caenorhabditis elegans.
The evolution of plasticity of dauer larva developmental arrest in the nematode Caenorhabditis elegans.
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DOI：
10.1002/ece3.1436
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发表时间：
2015-03
影响因子：
2.6
通讯作者：
Viney, Mark
中科院分区：
文献类型：
--
作者：
Diaz, S. Anaid;Viney, Mark
生物体可能最终处于不利的条件下，为了生存，它们进化出了各种策略。有些生物，包括线虫，通过发育停滞在不利的条件下生存。模式线虫秀丽隐杆线虫在两种幼虫形式之间具有发育选择，并且它选择在不利条件下（具体地，缺乏食物和高种群密度，由信息素的浓度指示）发育成被捕的幼虫形式。野生秀丽隐杆线虫分离株在其dauer幼虫捕获表型上差异很大，这就提出了一个问题，即是什么样的选择压力维持了这种表型多样性？为了研究这一点，我们在四种不同的环境中培养了秀丽隐杆线虫，这些环境由可以诱导幼虫发育的不同线索组合组成：在存在或不存在幼虫诱导信息素的情况下，食物浓度的两种组合（高和低）。五代的人工选择的dauer幼虫导致的dauer幼虫形成在大多数选择制度的整体增加。与不含信息素的环境相比，在环境中选择的信息素的存在下，达乌尔幼虫的数量增加了一倍。此外，只有高浓度的食物环境中含有信息素增加的可塑性dauer幼虫形成。这些进化反应也影响了蠕虫繁殖的时间。总的来说，这些结果让我们深入了解了可以选择秀丽隐杆线虫dauer幼虫停滞表型的不同可塑性的环境，这表明环境线索的不同组合可以选择秀丽隐杆线虫中所见的表型可塑性反应的多样性。
Organisms can end up in unfavourable conditions and to survive this they have evolved various strategies. Some organisms, including nematodes, survive unfavourable conditions by undergoing developmental arrest. The model nematode Caenorhabditis elegans has a developmental choice between two larval forms, and it chooses to develop into the arrested dauer larva form in unfavourable conditions (specifically, a lack of food and high population density, indicated by the concentration of a pheromone). Wild C. elegans isolates vary extensively in their dauer larva arrest phenotypes, and this prompts the question of what selective pressures maintain such phenotypic diversity? To investigate this we grew C. elegans in four different environments, consisting of different combinations of cues that can induce dauer larva development: two combinations of food concentration (high and low) in the presence or absence of a dauer larva-inducing pheromone. Five generations of artificial selection of dauer larvae resulted in an overall increase in dauer larva formation in most selection regimes. The presence of pheromone in the environment selected for twice the number of dauer larvae, compared with environments not containing pheromone. Further, only a high food concentration environment containing pheromone increased the plasticity of dauer larva formation. These evolutionary responses also affected the timing of the worms’ reproduction. Overall, these results give an insight into the environments that can select for different plasticities of C. elegans dauer larva arrest phenotypes, suggesting that different combinations of environmental cues can select for the diversity of phenotypically plastic responses seen in C. elegans.
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影响因子：
2.6
作者：
Diaz, S. Anaid;Viney, Mark
通讯作者：
Viney, Mark
比较代谢组学揭示了丙烷剂的生物发生，这是秀丽隐杆线虫中小分子信号的模块化库。
影响因子：
15
作者：
von Reuss, Stephan H.;Bose, Neelanjan;Srinivasan, Jagan;Yim, Joshua J.;Judkins, Joshua C.;Sternberg, Paul W.;Schroeder, Frank C.
通讯作者：
Schroeder, Frank C.
影响因子：
--
作者：
Petersen C;Dirksen P;Prahl S;Strathmann EA;Schulenburg H
通讯作者：
Schulenburg H
影响因子：
3.4
作者：
Diaz SA;Brunet V;Lloyd-Jones GC;Spinner W;Wharam B;Viney M
通讯作者：
Viney M
DOI：
10.1895/wormbook.1.155.1
发表时间：
2013-01-18
期刊：
WormBook : the online review of C. elegans biology
影响因子：
--
作者：
Ludewig AH;Schroeder FC
通讯作者：
Schroeder FC