Polycystic Ovary Syndrome and the Forgotten Uterus.
Polycystic Ovary Syndrome and the Forgotten Uterus.
复制标题
DOI：
10.1016/j.xfnr.2020.12.001
复制
发表时间：
2021-01
期刊：
影响因子：
--
通讯作者：
Blesson CS
中科院分区：
文献类型：
--
作者：
Hosseinzadeh P;Barsky M;Gibbons WE;Blesson CS
多囊卵巢综合征（PCOS）是一种常见的疾病，影响生育的各个方面。虽然卵巢和代谢方面的疾病是很好的研究，其在子宫功能障碍的作用还没有得到很好的理解。我们的目的是审查的特点，子宫内膜和子宫异常的妇女多囊卵巢综合征。在PubMed、Medline和科克伦图书馆数据库中对截至2020年3月以英语发表的论文进行了系统性文献检索。使用以下关键词进行检索：多囊卵巢综合征、多囊卵巢疾病、多囊卵巢、PCOS、PCOD、PCO、PCOM、排卵过少、无排卵、月经过少、闭经、高雄激素血症，并结合术语：子宫内膜、不孕、子宫、孕酮抵抗、子宫内膜增生、妊娠结局、早产。在这篇综述中，我们强调了与PCOS相关的各种子宫病理学，并探讨其对生育能力的影响。我们还讨论了多囊卵巢综合征中可能与不孕、子宫内膜增生和癌症有关的关键子宫分子通路的改变。
Polycystic ovary syndrome (PCOS) is a common disorder that affects various facets of fertility. Although the ovarian and metabolic aspects of the disease is well studied, its role in uterine dysfunction is not well understood. Our objective was to review the features of endometrial and uterine aberrations in women with PCOS. A systematic literature search was performed in PubMed, Medline, and the Cochrane Library databases for papers published in English up to March 2020. The following key words were used for the search: polycystic ovary syndrome, poly cystic ovarian disease, polycystic ovaries, PCOS, PCOD, PCO, PCOM, oligoovulation, anovulation, oligomenorrhea, amenorrhea, hyperandrogenism and this was combined with terms; endometrium, infertility, uterus, progesterone resistance, endometrial hyperplasia, pregnancy outcomes, preterm delivery. In this review, we highlight various uterine pathologies that are associated with PCOS and explore its impact on fertility. We also discuss key uterine molecular pathways that are altered in PCOS that may be related to infertility, endometrial hyperplasia and cancer.
登录
查看更多内容
影响因子：
82.9
作者：
Cha J;Sun X;Dey SK
通讯作者：
Dey SK
影响因子：
2.3
作者：
Fearnley, Emily J.;Marquart, Louise;Webb, Penelope M.
通讯作者：
Webb, Penelope M.
影响因子：
5.2
作者：
Bruchim I;Sarfstein R;Werner H
通讯作者：
Werner H
影响因子：
6.7
作者：
Franasiak, Jason M.;Holoch, Kristin J.;Yuan, Lingwen;Schammel, David P.;Young, Steven L.;Lessey, Bruce A.
通讯作者：
Lessey, Bruce A.
影响因子：
3.5
作者：
Dal Maso, L;Augustin, LSA;La Vecchia, C
通讯作者：
La Vecchia, C