Discrete coding of stimulus value, reward expectation, and reward prediction error in the dorsal striatum.
Discrete coding of stimulus value, reward expectation, and reward prediction error in the dorsal striatum.
复制标题
背侧纹状体刺激值、奖励期望和奖励预测误差的离散编码。
DOI:
10.1152/jn.00097.2015
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发表时间:
2015
影响因子:
2.5
通讯作者:
Tsutsui KI
中科院分区:
文献类型:
--
作者:
Oyama K;Tateyama Y;Hernadi I;Tobler PN;Iijima T;Tsutsui KI
To investigate how the striatum integrates sensory information with reward information for behavioral guidance, we recorded single-unit activity in the dorsal striatum of head-fixed rats participating in a probabilistic Pavlovian conditioning task with auditory conditioned stimuli (CSs) in which reward probability was fixed for each CS but parametrically varied across CSs. We found that the activity of many neurons was linearly correlated with the reward probability indicated by the CSs. The recorded neurons could be classified according to their firing patterns into functional subtypes coding reward probability in different forms such as stimulus value, reward expectation, and reward prediction error. These results suggest that several functional subgroups of dorsal striatal neurons represent different kinds of information formed through extensive prior exposure to CS-reward contingencies.
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