The high-efficiency synergistic and broad-spectrum antibacterial effect of cobalt doped zinc oxide quantum dots (Co-ZnO QDs) loaded cetyltributylphosphonium bromide (CTPB) modified MMT (C-MMT) nanocomposites

The high-efficiency synergistic and broad-spectrum antibacterial effect of cobalt doped zinc oxide quantum dots (Co-ZnO QDs) loaded cetyltributylphosphonium bromide (CTPB) modified MMT (C-MMT) nanocomposites
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钴掺杂氧化锌量子点(Co-ZnO QDs)负载十六烷基三丁基溴化鏻(CTPB)修饰蒙脱土(C-MMT)纳米复合材料的高效协同广谱抗菌作用

DOI:
10.1016/j.colsurfa.2020.126059
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发表时间:
2021-03
期刊:
Colloids and Surfaces A: Physicochemical and Engineering Aspects
影响因子:
--
通讯作者:
Aiqin Wang
Aiqin Wang
中科院分区:
其他
文献类型:
--
作者:
Junli Liu;Yuhan Wang;Xiuyi Fan;Hui Liu;Junqi Li;Xuanmeng He;Aiping Hui;Aiqin Wang

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以十六烷基三丁基溴化磷(CTPB)改性蒙脱土(C-MMT)为载体,采用化学沉淀法制备了Co-ZnO量子点/C-MMT纳米复合材料。TEM和SEM结果表明,Co-ZnO量子点可以吸附在C-MMT表面,甚至嵌入到C-MMT的层状结构中。抗菌性能测试结果表明,1 mL 3.0 mg mL− 1 Co-ZnO QDs/C-MMT复合材料对革兰氏阴性菌大肠杆菌、革兰氏阳性菌金黄色葡萄球菌和真菌黄曲霉的抑制率分别达到97.9%、95.6%和88.0%。EPR、TEM和吸附实验表明,Co-ZnO QDs/C-MMT纳米复合材料结合了Co-ZnO QDs的高活性氧生成能力和C-MMT、Co-ZnO QDs的优良细菌吸附能力,具有靶向性和高效抗菌活性,有望成为一种新型抗菌剂。
Co-ZnO QDs/C-MMT nanocomposites is prepared via a facile chemical precipitation method with cetyltributylphosphonium bromide (CTPB) modified MMT (C-MMT) as the carrier. TEM and SEM results show that Co-ZnO QDs could be absorbed on the surface of C-MMT, even embedded into the layered structures of C-MMT. Antibacterial performances showed the inhibition rate of 1 mL 3.0 mg mL−1Co-ZnO QDs/C-MMT composites to Gram-negative bacteriaEscherichia coli, Gram-positive bacteriaStaphylococcus aureusand fungiAspergillus flavuscould reach to 97.9 %, 95.6 % and 88.0 %, respectively. EPR results, TEM analysis and adsorption experiment indicated that Co-ZnO QDs/C-MMT nanocomposites, combining the high ROS production of Co-ZnO QDs and excellent bacteria-adsorbed capability of C-MMT and Co-ZnO QDs, thus display specific-targeting capability, high-efficiency antibacterial activity, suggesting the potential application as a novel antibacterial agent.
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