Marijuana and spontaneous abortion of known karyotype.
Marijuana and spontaneous abortion of known karyotype.
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大麻和已知核型的自然流产。
DOI：
10.1111/j.1365-3016.1991.tb00717.x
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发表时间：
1991
影响因子：
2.8
通讯作者：
Warburton,D
中科院分区：
文献类型：
--
作者：
Kline,J;Hutzler,M;Levin,B;Stein,Z;Susser,M;Warburton,D
We tested whether marijuana use in the 2 months before the last menstrual period and during pregnancy affects the risk of spontaneous abortions of known karyotype. Spontaneous abortions (cases) were defined as chromosomally normal (n= 567) or chromosomally aberrant (n= 393) and, within the latter, by type of aberration (212 trisomies, 71 monosomies X, 49 triploidies, 61 others). Controls were women with prenatal care before 22 weeks gestation and delivering at 28 weeks or later (n= 2042). In comparison with controls, adjusted odds (OR) of reported marijuana use in chromosomally normal cases were 1.1 (95% confidence interval (CI) 0.7, 1.5) and in chromosomally aberrant cases combined 1.2(95% CI 0.7,1.9). With respect to specific aberrations, use in the perifertilisation period did not differ significantly from that in controls for trisomies (adjusted OR = 0.8, 95% CI 0.4, 1.8), monosomies X (adjusted OR = 1.8, 95% CI0.7, 4.3), and triploidies (adjusted OR = 1.3, 95%) CI 0.4, 4.5). Comparisons of karyotype groups with each other yielded similar results. Our data do not support causal associations of marijuana use, at the levels represented in our sample, with either chromosomally normal or trisomic spontaneous abortion. With monosomy X and triploidy, no statistically significant associations were detected although numbers were insufficient to rule out moderate effects.
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自然流产作为筛查手段。
影响因子：
5
作者：
Z. Stein;M. Susser;D. Warburton;J. Wittes;J. Kline
通讯作者：
J. Kline
受孕到出生：产前发育的流行病学
DOI：
--
发表时间：
1989
期刊：
影响因子：
--
作者：
J. Kline;Z. Stein;M. Susser
通讯作者：
M. Susser
DOI：
10.1016/s0163-1047(80)90469-0
发表时间：
1980-01-01
期刊：
BEHAVIORAL AND NEURAL BIOLOGY
影响因子：
--
作者：
ABEL, EL
通讯作者：
ABEL, EL
影响因子：
5
作者：
J. Kline;Z. Stein;B. Strobino;M. Susser;D. Warburton
通讯作者：
D. Warburton
人工流产和随后流产（自然流产）的染色体特征。
影响因子：
5
作者：
J. Kline;Z. Stein;M. Susser;D. Warburton
通讯作者：
D. Warburton