Size control during organogenesis: Development of the lateral line organs in zebrafish
Size control during organogenesis: Development of the lateral line organs in zebrafish
复制标题
器官发生过程中的大小控制:斑马鱼侧线器官的发育
DOI:
10.1111/dgd.12196
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发表时间:
2015
期刊:
影响因子:
--
通讯作者:
K.
中科院分区:
文献类型:
--
作者:
Wada;H. and Kawakami;K.
Many genes that play essential roles in organ growth have been identified across a range of organisms. However, the mechanisms by which growing organs can sense their sizes and stop growing when they reach their proper sizes remain poorly understood. The mechanosensory organs of the fish lateral line system (neuromasts) provide an ideal system to address this question for the following reasons. First, each superficial neuromast is composed of a small number of cells situated on the body surface, making it relatively easy to quantify organ size throughout development. Second, while the sensory cells of superficial neuromasts are continuously renewed, overall organ size is homeostatically maintained. Third, there is another type of neuromast showing an opposite mode of growth: that is, canal neuromasts increase in size in proportion to organism body size. Here, we review recent findings regarding the mechanisms that control organ size in the zebrafish lateral line.
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影响因子:
--
作者:
S. W. Bailey
通讯作者:
S. W. Bailey
DOI:
--
发表时间:
1998
期刊:
影响因子:
--
作者:
A. Quilhac;J. Sire
通讯作者:
J. Sire
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
Wada;H.;Kawakami;K.
通讯作者:
K.
DOI:
--
发表时间:
1989
期刊:
影响因子:
--
作者:
E. Denton;J. Gray
通讯作者:
J. Gray
DOI:
10.1073/pnas.1202774109
发表时间:
2012-05-22
影响因子:
11.1
作者:
Chai, Renjie;Kuo, Bryan;Cheng, Alan G.
通讯作者:
Cheng, Alan G.