Alcohol, Drinking Pattern, and Chronic Disease.
Alcohol, Drinking Pattern, and Chronic Disease.
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DOI：
10.3390/nu14091954
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发表时间：
2022-05-07
期刊：
影响因子：
5.9
通讯作者：
Martinez-Gonzalez, Miguel A.
中科院分区：
文献类型：
--
作者：
Barberia-Latasa, Maria;Gea, Alfredo;Martinez-Gonzalez, Miguel A.
关键词：
本综述讨论了关于饮酒及其与慢性病相关性的不一致建议，强调了基于证据的共识的必要性。酒精是一种成瘾性物质，在世界范围内消费，特别是在欧洲国家。关于饮酒的建议存在争议。一方面，许多非随机研究认为，适度消费具有有益的心血管效应或降低全因死亡率的风险。另一方面，酒精与癌症、神经系统疾病或损伤等风险增加有关。多年来，人们一直在努力回答关于酒精摄入量的安全问题，但争议仍然存在。观察性研究提倡适度饮酒遵循地中海模式（红酒与膳食避免狂饮）作为当前饮酒者的最佳选择。然而，IARC等机构建议避免饮酒，因为它是一种强致癌物。在此背景下，应开展更多的随机试验、更大的样本量和硬临床终点，以澄清现有证据，并为临床医生的临床实践提供支持。
This review discusses the inconsistent recommendations on alcohol consumption and its association with chronic disease, highlighting the need for an evidence-based consensus. Alcohol is an addictive substance consumed worldwide, especially in European countries. Recommendations on alcohol consumption are controversial. On one hand, many nonrandomized studies defend that moderate consumption has a beneficial cardiovascular effect or a lower risk of all-cause mortality. On the other hand, alcohol is associated with an increased risk of cancer, neurological diseases, or injuries, among others. For years, efforts have been made to answer the question regarding the safe amount of alcohol intake, but controversies remain. Observational studies advocate moderate alcohol consumption following a Mediterranean pattern (red wine with meals avoiding binge drinking) as the best option for current drinkers. However, agencies such as the IARC recommend abstention from alcohol as it is a potent carcinogen. In this context, more randomized trial with larger sample size and hard clinical endpoints should be conducted to clarify the available evidence and provide clinicians with support for their clinical practice.
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影响因子：
2.9
作者：
Yang JH;Jeong JA;Kweon SS;Lee YH;Choi SW;Ryu SY;Nam HS;Park KS;Kim HY;Shin MH
通讯作者：
Shin MH
DOI：
10.1136/bmj.h4238
发表时间：
2015-08-18
期刊：
BMJ (Clinical research ed.)
影响因子：
--
作者：
Cao Y;Willett WC;Rimm EB;Stampfer MJ;Giovannucci EL
通讯作者：
Giovannucci EL
DOI：
10.1136/bmj.d636
发表时间：
2011-02-22
期刊：
BMJ (Clinical research ed.)
影响因子：
--
作者：
Brien SE;Ronksley PE;Turner BJ;Mukamal KJ;Ghali WA
通讯作者：
Ghali WA
影响因子：
3.5
作者：
Ahmed, A. T.;Karter, A. J.;Liu, J.
通讯作者：
Liu, J.
影响因子：
5.7
作者：
Ahmed, Ameena T.;Karter, Andrew J.;Weisner, Constance M.
通讯作者：
Weisner, Constance M.